Semiconductor Electronic Label-Free Assay for Predictive Toxicology. [PDF]
, 2016 While animal experimentations have spearheaded numerous breakthroughs in biomedicine, they also have spawned many logistical concerns in providing toxicity screening for copious new materials. Their prioritization is premised on performing cellular-level
Chui, Chi On +5 more
core +2 more sources
Label-free electrochemical monitoring of DNA ligase activity [PDF]
, 2008 This study presents a simple, label-free electrochemical technique for the monitoring of DNA ligase activity. DNA ligases are enzymes that catalyze joining of breaks in the backbone of DNA and are of significant scientific interest due to their essential
Ahel I. +29 more
core +1 more source
Label-Free Metabolic Classification of Single Cells in Droplets Using the Phasor Approach to Fluorescence Lifetime Imaging Microscopy. [PDF]
, 2019 Characterization of single cell metabolism is imperative for understanding subcellular functional and biochemical changes associated with healthy tissue development and the progression of numerous diseases.
Aghaamoo, Mohammad +4 more
core +1 more source
Extracting histones for the specific purpose of label-free MS [PDF]
, 2016 Extracting histones from cells is the first step in studies that aim to characterize histones and their post-translational modifications (hPTMs) with MS.
De Clerck, Laura +9 more
core +2 more sources
Label-free receptor assays [PDF]
Drug Discovery Today: Technologies, 2010 Label-free biosensors offer integrated, kinetic and multi-parametric measures of receptor biology and ligand pharmacology in whole cells. Being highly sensitive and pathway-unbiased, label-free receptor assays can be used to probe the systems cell biology including pleiotropic signaling of receptors, and to characterize the functional selectivity and ...
openaire +3 more sources
Metamaterial-based label-free optical biosensing
Cailiao gongcheng, 2021 Metamaterials have drawn extensive attention for their fine regulation of electromagnetic waves at subwavelength scales. They have abundant electromagnetic modes, and support highly confined and enhanced electromagnetic fields on the surface which are ...
TAO Cheng-dong +5 more
doaj +1 more source
High-resolution Imaging of nanoparticles in wide-field interferometric scattering microscopy [PDF]
, 2019 Single particle interferometric scattering microscopy has demonstrated great capability in label-free imaging of sub-wavelength dielectric nanoparticles ...
Avci, Oguzhan +5 more
core +1 more source
Advancing liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry toward ultra-high-throughput analysis [PDF]
, 2020 Label-free high-throughput screening using mass spectrometry has the potential to provide rapid large-scale sample analysis at a speed of more than one sample per second.
Brown, Jeffery +5 more
core +1 more source
Label-free, single molecule detection of cytokines using optical microcavities [PDF]
, 2007 Interleukin-2 (IL2) is a cytokine that regulates T-cell growth and is used in cancer therapies. By sensitizing a microcavity sensor surface with anti-IL2 and monitoring the resonant frequency, single molecules of IL2 can be ...
Armani, Andrea M. +2 more
core +1 more source
Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements [PDF]
, 2010 Label-free biosensor technology based on dynamic mass redistribution (DMR) of cellular constituents promises to translate GPCR signaling into complex optical 'fingerprints' in real time in living cells.
Blattermann, S +16 more
core +1 more source