Results 31 to 40 of about 518,105 (292)

Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling [PDF]

open access: yes, 2014
<b>Background:</b>  Proteomics-based approaches for biomarker discovery are promising strategies used in cancer research. We present state-of-art label-free quantitative proteomics method to assess proteome of renal cell carcinoma (RCC ...
Atrih, A.   +8 more
core   +4 more sources

High-throughput, nonperturbing quantification of lipid droplets with digital holographic microscopy

open access: yesJournal of Lipid Research, 2018
In vitro differentiating adipocytes are sensitive to liquid manipulations and have the tendency to float. Assessing adipocyte differentiation using current microscopy techniques involves cell staining and washing, while using flow cytometry involves cell
Vasco Campos   +4 more
doaj   +1 more source

Label-free photoacoustic ophthalmic angiography [PDF]

open access: yesOptics Letters, 2009
We present label-free functional photoacoustic imaging of the ocular microvasculature in living animals. The anterior segment of an adult mouse was imaged with a laser exposure level well within the American National Standards Institute safety standards.
Hu, Song   +3 more
openaire   +3 more sources

Ultrasensitive Label-Free Nanosensing and High-Speed Tracking of Single Proteins [PDF]

open access: yes, 2016
: Label-free detection, analysis, and rapid tracking of nanoparticles is crucial for future ultrasensitive sensing applications, ranging from understanding of biological interactions to the study of size-dependent classical-quantum transitions.
Hugall, James T.   +2 more
core   +5 more sources

Label-Free Optical Resonator-Based Biosensors

open access: yesSensors, 2020
The demand for biosensor technology has grown drastically over the last few decades, mainly in disease diagnosis, drug development, and environmental health and safety.
Donggee Rho   +2 more
doaj   +1 more source

Comparison of a Label-Free Quantitative Proteomic Method Based on Peptide Ion Current Area to the Isotope Coded Affinity Tag Method

open access: yesCancer Informatics, 2008
Recently, several research groups have published methods for the determination of proteomic expression profiling by mass spectrometry without the use of exogenously added stable isotopes or stable isotope dilution theory.
Young Ah Goo   +5 more
doaj   +2 more sources

Label-Free Ultrasensitive Memristive Aptasensor [PDF]

open access: yesNano Letters, 2016
We present the very first worldwide ever-reported electrochemical biosensor based on a memristive effect and DNA aptamers. This novel device is developed to propose a completely new approach in cancer diagnostics. In this study, an affinity-based technique is presented for the detection of the prostate specific antigen (PSA) using DNA aptamers.
Tzouvadaki, Ioulia   +6 more
openaire   +3 more sources

Silicon nanophotonic ring resonators sensors integrated in reaction tubes [PDF]

open access: yes, 2013
Enzyme-linked immunosorbent assays (ELISA) are the most popular immunoassay techniques performed every day in hospitals and laboratories and they are used as a diagnostic tool in medicine and plant pathology, as well as a quality-control check in various
Bienstman, Peter   +6 more
core   +1 more source

Comparison of label‐free and label‐based approaches for surface‐enhanced Raman microscopic imaging of bacteria cells

open access: yesAnalytical Science Advances, 2020
Surface‐enhanced Raman spectroscopic (SERS) approaches are emerging for bacteria analysis whereby bacteria cells can be measured based on their biochemical composition (label‐free) or with the aid of a chemical label to enhance the SERS signal. Combining
Michael E. Hickey, Siyue Gao, Lili He
doaj   +1 more source

Design rules for combined label-free and fluorescence Bloch surface wave biosensors [PDF]

open access: yes, 2017
We report on the fabrication and physical characterization of optical biosensors implementing simultaneous label-free and fluorescence detection and taking advantage of the excitation of Bloch surface waves at a photonic crystal’s truncation interface ...
Christoph, Wächter   +5 more
core   +1 more source

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