Results 131 to 140 of about 330,705 (346)

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

open access: yesAdvanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard   +7 more
wiley   +1 more source

Effect of CYP2C19 status on platelet reactivity in Taiwanese acute coronary syndrome patients switching to prasugrel from clopidogrel: Switch Study

open access: yesJournal of the Formosan Medical Association, 2022
Background/Purpose: Pharmacogenetics is a potential driver of the “East Asian paradox,” in which East Asian acute coronary syndrome (ACS) patients receiving dual antiplatelet therapy (DAPT) with clopidogrel following percutaneous coronary intervention ...
Feng-Yu Kuo   +15 more
doaj  

Generation of Advanced Blood–Brain Barrier Spheroids Using Human‐Induced Pluripotent Stem Cell‐Derived Brain Capillary Endothelial‐Like Cells

open access: yesAdvanced Biology, EarlyView.
In this article, the establishment and characterization of a self‐assembled 3D BBB spheroid model using human induced pluripotent stem cell (hiPSC)‐derived and primary cells is reported. Spheroids demonstrate in‐vivo like tight junction ultrastructure and, in comparison to 2D mono‐cultures, higher transcript expression of BBB specific genes.
Sanjana Mathew‐Schmitt   +10 more
wiley   +1 more source

Switching off the label 'women in tech'

open access: yes, 2020
The focus of the talk is on the ways in which women are discursively constructed in the context of professional spaces in tech clusters. This is to give time to consider how the label "women in tech" (WiT) is dominated by the masculine perspective of tech work and characterised by how individuals perform "identity work". It has become apparent that the
openaire   +1 more source

Light‐Triggered Protease‐Mediated Release of Actin‐Bound Cargo from Synthetic Cells

open access: yesAdvanced Biology, EarlyView.
TEV Prtoease‐mediated Releasable Actin‐binding Protein (TRAP) is a protein‐based platform consisting of a cargo tightly bound to reconstituted actin networks in synthetic cells which can be proteolyticly released from the bound actin, followed by its secretion through membrane translocation mediated by a cell‐penetrating peptide.
Mousumi Akter   +3 more
wiley   +1 more source

Effects of switching from olanzapine to aripiprazole on the metabolic profiles of patients with schizophrenia and metabolic syndrome: a double-blind, randomized, open-label study [Corrigendum]

open access: yesNeuropsychiatric Disease and Treatment, 2015
Wani RA, Dar MA, Chandel RK, et al Title of paper should have been “Effects of switching from olanzapine to aripiprazole on the metabolic profiles of patients with schizophrenia and metabolic syndrome: a randomized, open-label study&rdquo ...
Wani RA   +6 more
doaj  

Contextualizing code-switching: testing the effects of reggaetón labels and listening frequency in an Acceptability Judgment Task

open access: yesFrontiers in Communication
This study presents an Acceptability Judgment Task (AJT) conducted with Latinx1 Spanish-English bilinguals in the United States. We take a social approach to the AJT by contextualizing code-switching (CS) within the context of reggaetón music by adding ...
Salvatore Callesano   +4 more
doaj   +1 more source

A label-free thrombin photoelectrochemical aptasensor based on structure-switching in G-quadruplexes

open access: yesBiosensors and Bioelectronics: X, 2022
In this work, an Au/GaN photoelectrode was prepared by sputtering a 30.0-nm–thick gold film on an n-type gallium nitride (GaN) surface. Guanine (G) was used as a hole trap in photoinduced charge separation due to its lowest oxidation potential and ...
Xiujun Rong   +9 more
doaj  

THE EFFECT OF NEW FOOD LABELING ON NUTRIENT INTAKES: AN ENDOGENOUS SWITCHING REGRESSION ANALYSIS [PDF]

open access: yes
This paper examines the effect of the new labeling regulations on nutrient intakes using an endogenous switching regression model. Using the 1994 - 96 CSFII/DHKS, we evaluate the impact of food label use on intakes of selected nutrients.Food Consumption ...
Capps, Oral, Jr.   +2 more
core   +1 more source

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