Results 51 to 60 of about 278,707 (295)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A label-free thrombin photoelectrochemical aptasensor based on structure-switching in G-quadruplexes

open access: yesBiosensors and Bioelectronics: X, 2022
In this work, an Au/GaN photoelectrode was prepared by sputtering a 30.0-nm–thick gold film on an n-type gallium nitride (GaN) surface. Guanine (G) was used as a hole trap in photoinduced charge separation due to its lowest oxidation potential and ...
Xiujun Rong   +9 more
doaj   +1 more source

Simulasi Multi Protocol Label Switching Virtual Private Network (MPLS VPN) Dengan Virtual Local Area Network (VLAN) Menggunakan Router MIKROTIK [PDF]

open access: yes, 2018
Untuk mendapatkan komunikasi yang cepat, aman, dan mudah diakses digunakan jaringan MPLS VPN menggunakan VLAN. Jaringan MPLS akan mengirimkan paket sesuai dengan label yang ada pada header paket ke tujuan yang diinginkan dan VPN akan membatasi siapa ...
Euginia, B. (Bertha)   +1 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Performance evaluation of MPLS-enabled communications infrastructure for wide area monitoring systems [PDF]

open access: yes, 2015
In order to obtain the transient power system measurement information, Wide Area Monitoring Systems (WAMS) should be able to collect Phasor Measurement Unit (PMU) data in a timely manner.
Ashton, PM   +3 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Silicon Photonics towards Disaggregation of Resources in Data Centers

open access: yesApplied Sciences, 2018
In this paper, we demonstrate two subsystems based on Silicon Photonics, towards meeting the network requirements imposed by disaggregation of resources in Data Centers.
Miltiadis Moralis-Pegios   +3 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Sistem Rekomendasi Hybrid Menggunakan Metode Switching

open access: yesJuTISI (Jurnal Teknik Informatika dan Sistem Informasi)
Perkembangan teknologi memaksa pelaku bisnis untuk memberikan layanan terbaik dengan menjadikan sistem rekomendasi sebagai salah satu solusi untuk menjaga loyalitas konsumen.
Muhammad Rizki, Rianto Rianto
doaj   +1 more source

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