Results 51 to 60 of about 330,705 (346)

Switching to riociguat: a potential treatment strategy for the management of CTEPH and PAH

Pulmonary Circulation, 2020
Currently, five classes of drug are approved for the treatment of pulmonary arterial hypertension (PAH): phosphodiesterase 5 inhibitors (PDE5i); endothelin receptor antagonists; prostacyclin analogs; the IP receptor agonist selexipag; and the soluble ...
Raymond L. Benza, Paul A. Corris, Hossein-Ardeschir Ghofrani, Manreet Kanwar, Vallerie V. McLaughlin, Amresh Raina, Gérald Simonneau   +6 more
doaj   +1 more source

Analysis of Kinetic Models for Label Switching and Stochastic Gradient Descent [PDF]

arXiv, 2022
In this paper we provide a novel approach to the analysis of kinetic models for label switching, which are used for particle systems that can randomly switch between gradient flows in different energy landscapes. Besides problems in biology and physics, we also demonstrate that stochastic gradient descent, the most popular technique in machine learning,
arxiv  

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

Multifunctional Switch Based on Spin-Labeled Gold Nanoparticles

Nano Letters, 2022
The fabrication of multifunctional switches is a fundamental step in the development of nanometer-scale molecular spintronic devices. The anchoring of active organic radicals on gold nanoparticles (AuNPs) surface is little studied and the realization of AuNPs-based switches remains extremely challenging.
Vega Lloveras, Pilar Elías-Rodríguez, Luca Bursi, Ehsan Shirdel, Alejandro R. Goñi, Arrigo Calzolari, José Vidal-Gancedo   +6 more
openaire   +5 more sources

ANALISA QUALITY OF SERVICE (QoS) JARINGAN MULTIPROTOCOL LABEL SWITCHING (MPLS) SEBAGAI PENERAPAN TEKNOLOGI INTERNET PROTOCOL (IP) [PDF]

, 2015
ABSTRAKSI: Multiprotocol Label Switching (MPLS) merupakan metode dengan unjuk kerja tinggi untuk proses forwarding data (frame) di sebuah jaringan. Konsep dari MPLS ini menggunakan switching node yang biasa disebut Label Switching Router (LSR).
AGUSTA ROMA DINATA
core  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Transformer-Transducers for Code-Switched Speech Recognition [PDF]

arXiv, 2020
We live in a world where 60% of the population can speak two or more languages fluently. Members of these communities constantly switch between languages when having a conversation. As automatic speech recognition (ASR) systems are being deployed to the real-world, there is a need for practical systems that can handle multiple languages both within an ...
arxiv  

Simulasi Multi Protocol Label Switching Virtual Private Network (MPLS VPN) Dengan Virtual Local Area Network (VLAN) Menggunakan Router MIKROTIK [PDF]

, 2018
Untuk mendapatkan komunikasi yang cepat, aman, dan mudah diakses digunakan jaringan MPLS VPN menggunakan VLAN. Jaringan MPLS akan mengirimkan paket sesuai dengan label yang ada pada header paket ke tujuan yang diinginkan dan VPN akan membatasi siapa ...
Euginia, B. (Bertha), Ghozali, T. (Theresia)   +1 more
core  

Adaptive MCMC with online relabeling

, 2015
When targeting a distribution that is artificially invariant under some permutations, Markov chain Monte Carlo (MCMC) algorithms face the label-switching problem, rendering marginal inference particularly cumbersome. Such a situation arises, for example,
Bardenet, Rémi, Cappé, Olivier, Fort, Gersende, Kégl, Balázs   +3 more
core   +3 more sources

All-optical label swapping of in-band addresses and 160 Gbit/s data packets [PDF]

, 2009
A 1×4 all-optical packet switch is presented, based on an optical label swapping technique that utilises a scalable label processor and a label rewriter with 'on the fly' operation.
Calabretta, N., Dorren, H.J.S., Herrera Llorente, J., Jung, H.D., Tangdiongga, E.   +4 more
core   +1 more source