Results 51 to 60 of about 2,887,200 (357)
Tunable 4-channel ultra-dense WDM demultiplexer with III-V photodiodes integrated in silicon-on-insulator [PDF]
, 2012 A tunable 4-channel ultra-dense WDM demultiplexer with 0.25nm channel spacing is demonstrated with III-V photodiodes integrated on Silicon-on-Insulator using rib waveguides.
De Heyn, Peter +4 more
core
Optimizing segment routing using evolutionary computation [PDF]
, 2017 Segment Routing (SR) combines the simplicity of Link-State routing protocols with the flexibility of Multiprotocol Label Switching (MPLS). By decomposing forwarding paths into segments, identified by labels, SR improves Traffic Engineering (TE) and ...
McKeown +6 more
core +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Switching to riociguat: a potential treatment strategy for the management of CTEPH and PAH
Pulmonary Circulation, 2020 Currently, five classes of drug are approved for the treatment of pulmonary arterial hypertension (PAH): phosphodiesterase 5 inhibitors (PDE5i); endothelin receptor antagonists; prostacyclin analogs; the IP receptor agonist selexipag; and the soluble ...
Raymond L. Benza +6 more
doaj +1 more source
Vaccines, 2022 Kidney transplant recipients (KTRs) have a suboptimal immune response to COVID-19 vaccination due to the effects of immunosuppression, mostly mycophenolic acid (MPA).
Athiphat Banjongjit +12 more
doaj +1 more source
FEBS Letters, EarlyView.Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source
Relabelling Algorithms for Large Dataset Mixture Models [PDF]
, 2014 Mixture models are flexible tools in density estimation and classification problems. Bayesian estimation of such models typically relies on sampling from the posterior distribution using Markov chain Monte Carlo.
Fan, Yanan, Zhu, Wanchuang
core
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Journal of the Formosan Medical Association, 2022 Background/Purpose: Pharmacogenetics is a potential driver of the “East Asian paradox,” in which East Asian acute coronary syndrome (ACS) patients receiving dual antiplatelet therapy (DAPT) with clopidogrel following percutaneous coronary intervention ...
Feng-Yu Kuo +15 more
doaj +1 more source