Results 71 to 80 of about 58,664 (301)

Subcutaneous Sarilumab in Patients With Rheumatoid Arthritis who Previously Received Subcutaneous Sarilumab or Intravenous Tocilizumab: An Open‐Label Extension of a Randomized Clinical Trial

open access: yesACR Open Rheumatology, 2020
Objective This post hoc analysis evaluated the safety and efficacy of open‐label sarilumab in patients with rheumatoid arthritis (RA) who completed the phase III double‐blind ASCERTAIN study (NCT01768572) and switched from intravenous (IV) tocilizumab to
Paul Emery   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Performance analysis of 112 Gb/s×4-channel WDM PDM-DQPSK optical label switching system with spectral amplitude code labels

open access: yesPhotonic Sensors, 2016
We present the performance analysis of 112 Gb/s×4 wavelength division multiplexing (WDM) 100 GHz channel spacing polarization division multiplexed-differential quadrature phase shift keying (PDM-DQPSK) optical label switching system with frequency swept ...
Isaac Adjaye Aboagye   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Alleviating Label Switching with Optimal Transport

open access: yesCoRR, 2019
33rd Conference on Neural Information Processing Systems (NeurIPS 2019), Vancouver ...
Monteiller, Pierre   +5 more
openaire   +4 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Support For IP Mobility and Diversity in a Broadband Wireless Access Network [PDF]

open access: yes, 2010
Broadband wireless access (BWA) network working at millimetre bands possesses the advantages of quick deployment, more flexibility, wide service coverage and cost efficiency.
Shi, Xyiu
core  

Cache Replacement Schemes for Data-Driven Label Switching Networks [PDF]

open access: yes, 2020
-The traffic on the Internet has been growing exponentially for some time. This growth is beginning to put stress on the current-day routers. On the other hand, switching technology, such as ATM, offers much higher performance than IP routing, but it is ...
Sungkee Jean   +3 more
core  

Asymmetric label switching resists binary imbalance [PDF]

open access: yes, 2020
In this correspondence, an asymmetric version of the label switching technique to build binary classification ensembles is introduced. The new version presents one more design parameter, the degree of asymmetry, and, consequently, it is more flexible to ...
Gutiérrez López, Aitor   +2 more
core   +1 more source

Comprehensive Downtime Prediction in Next-Generation Internet

open access: yesInternational Islamic University Malaysia Engineering Journal, 2012
The benchmark for the reliability quality of networks depends mainly on the accuracy and comprehensiveness of the reliability parameters. Downtime prediction of a communication system is crucial for the quality of service (QoS) offered to the end-user ...
W. F. Al-Khateeb, S. Al-Irhayim, and K. A. Al-Khateeb
doaj   +1 more source

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