Results 61 to 70 of about 58,664 (301)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Label-controlled optical switching nodes [PDF]

open access: yes, 2006
Optical networks are evolving from initially static optical circuits and subsequently optical circuit switching towards optical packet switching in order to take advan- tage of the high transport capacity made available by WDM systems in a more °exible ...
Vegas Olmos, J.J.
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Silicon Photonics towards Disaggregation of Resources in Data Centers

open access: yesApplied Sciences, 2018
In this paper, we demonstrate two subsystems based on Silicon Photonics, towards meeting the network requirements imposed by disaggregation of resources in Data Centers.
Miltiadis Moralis-Pegios   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Analysis of RSVP-TE graceful restart [PDF]

open access: yes, 2007
GMPLS is viewed as an attractive intelligent control plane for different network technologies and graceful restart is a key technique in ensuring this control plane is resilient and able to recover adequately from faults. This paper analyses the graceful
J. Sventek   +3 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Two‐mode multiplexed Fourier‐based labels

open access: yesElectronics Letters
A two‐mode optical packet switching architecture using an optical multiport mode‐division multiplexing label generator and processor is proposed. By combining optical labels on two modes, the number of labels is increased exponentially.
Takahiro Kodama, Gabriella Cincotti
doaj   +1 more source

Sistem Rekomendasi Hybrid Menggunakan Metode Switching

open access: yesJuTISI (Jurnal Teknik Informatika dan Sistem Informasi)
Perkembangan teknologi memaksa pelaku bisnis untuk memberikan layanan terbaik dengan menjadikan sistem rekomendasi sebagai salah satu solusi untuk menjaga loyalitas konsumen.
Muhammad Rizki, Rianto Rianto
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

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