Results 101 to 110 of about 2,514,522 (357)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Downstream labeling and upstream price competition [PDF]

open access: yes
The paper analyses the economic consequences of labeling in a setting with two vertically related markets. Labeling on the downstream market affects upstream price competition through two effects : a differentiation effect and a ranking effect.
Bonroy, O., Lemarié, S.
core  

PRODUCTOS AGROALIMENTARIOS DE CALIDAD COMO MECANISMO DE PROTECCIÓN DE PRODUCTORES Y DE CONSUMIDORES. [PDF]

open access: yesRevista Internacional de Doctrina y Jurisprudencia, 2014
For regulation of the hallmarks of quality wine, the European Union has approved a list of rules on the protection, production, labeling and control that protect those names. This article makes an analysis on the subject.
Ángel Sánchez Hernández
doaj  

Labeling Extracellular Vesicles for Nanoscale Flow Cytometry

open access: yesScientific Reports, 2017
Extracellular vesicles (EVs), including exosomes and microvesicles, are 30–800 nm vesicles that are released by most cell types, as biological packages for intercellular communication. Their importance in cancer and inflammation makes EVs and their cargo
A. Morales-Kastresana   +16 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Node Labeling

open access: yes, 1997
This document describes a scheme for labeling a program dependence graph (PDG) or control flow graph (CFG) in order to codify the hierarchical control dependence structure of a procedure. The first section describes the scheme and its features. Section 2
Chris J. Newburn, Node Labeling
core  

Superpixel labeling for medical image segmentation [PDF]

open access: yes, 2023
openNowadays, most methods for image segmentation consider images in a pixel- wise manner, which is a huge job and also time-consuming. On the other hand, superpixel labeling can make the segmentation task easier in some aspects. First, superpixels carry
REZAEI, SOMAYEH
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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