Results 81 to 90 of about 954,983 (314)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Downstream labeling and upstream price competition [PDF]
The paper analyses the economic consequences of labeling in a setting with two vertically related markets. Labeling on the downstream market affects upstream price competition through two effects : a differentiation effect and a ranking effect.
Bonroy, O., Lemarié, S.
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
PRODUCTOS AGROALIMENTARIOS DE CALIDAD COMO MECANISMO DE PROTECCIÓN DE PRODUCTORES Y DE CONSUMIDORES. [PDF]
Revista Internacional de Doctrina y Jurisprudencia, 2014 For regulation of the hallmarks of quality wine, the European Union has approved a list of rules on the protection, production, labeling and control that protect those names. This article makes an analysis on the subject.
Ángel Sánchez Hernández
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
THE WELFARE CONSEQUENCES OF CERTIFIED LABELING FOR CREDENCE ATTRIBUTES [PDF]
Certified labeling for credence attributes is examined using the concepts of pooled and separating equilibria. The analysis addresses a latent credence good demand that differs from a conventional good demand by willingness to pay for the credence ...
Hoehn, John P., Deaton, Brady J., Jr.
core
Multi-argument classification for semantic role labeling [PDF]
, 2008 This paper describes a Multi-Argument Classification (MAC) approach to Semantic Role Labeling. The goal is to exploit dependencies between semantic roles by simultaneously classifying all arguments as a pattern.
Smith, Tony C., Lin, Chi-San Althon
core +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
STRATEGIC LABELING AND TRADE OF GMOS [PDF]
This paper systematically analyzes the strategic effects of national regulatory decisions on labeling of GM products and identifies the determinants of the non-cooperative Nash equilibrium labeling regimes in a small number of producing countries that ...
Veyssiere, Luc, Giannakas, Konstantinos
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source