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Fair Hearing in Administrative Rule-Making: A Recent Experience Under the Federal Food, Drug, and Cosmetic and Fair Packaging and Labeling Acts [PDF]
, 1968 In promulgating regulations to govern the labeling of foods under the Fair Packaging and Labeling Act, the Commissioner of Food and Drugs, despite the objections of adversely affected parties, denied all requests for a public hearing. In this article the
Forte, Wesley E.
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Клиническая и экспериментальная тиреоидология, 2017 The article discusses the problems of modern clinical, laboratory and visual diagnostics, in particular the problem of reference ranges, high prevalence of clinically insignificant abnormalities with the increasing risk of detection when the tests are ...
Valentin V. Fadeyev
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Comparison of Different Labeling Techniques for the LC-MS Profiling of Human Milk Oligosaccharides
Frontiers in Chemistry, 2021 Human milk oligosaccharides (HMOs) exhibit various biological activities for infants, such as serving as prebiotics, blocking pathogens, and aiding in brain development.
Yinzhi Lang +9 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Nature CommunicationsFluorescent probes enable precise visualization of dynamic cellular processes, especially when combined with super-resolution imaging techniques that overcome the diffraction limit.
Marie Auvray +4 more
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Pharmaceuticals, 2016 Human CK2 is a heterotetrameric constitutively active serine/threonine protein kinase and is an emerging target in current anti-cancer drug discovery. The kinase is composed of two catalytic CK2α subunits and two regulatory CK2β subunits.
Christian Nienberg +5 more
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The Social Marginalization of People Living with a Mentally Ill Label–Family, Friends, and Work
Qualitative Sociology Review, 2021 This paper is based on qualitative research among people diagnosed with a mental illness who voluntarily attend a mental health center. Such individuals are given a degrading “mentally ill” label, which transforms them into a “new” person.
Kateřina Maloušková, Martin Fafejta
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Legal aspects of development of organic agriculture in Ukraine in the context of European integration [PDF]
Ekonomika Poljoprivrede (1979), 2020 In modern economic conditions, organic production is gaining global significance, partly addressing food security and contributing to the well-being of the population. Ukraine is in the top-20 of world leaders in the organic movement. In this regard, the
Ignatenko Iryna
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