Results 51 to 60 of about 728,673 (266)

Biocompatible sulfonium-based covalent probes for endogenous tubulin fluorescence nanoscopy in live and fixed cells

Nature Communications
Fluorescent probes enable precise visualization of dynamic cellular processes, especially when combined with super-resolution imaging techniques that overcome the diffraction limit.
Marie Auvray, Tanja Koenen, Olexandr Dybkov, Henning Urlaub, Gražvydas Lukinavičius   +4 more
doaj   +1 more source

Site-Specific Labeling of Protein Kinase CK2: Combining Surface Display and Click Chemistry for Drug Discovery Applications

Pharmaceuticals, 2016
Human CK2 is a heterotetrameric constitutively active serine/threonine protein kinase and is an emerging target in current anti-cancer drug discovery. The kinase is composed of two catalytic CK2α subunits and two regulatory CK2β subunits.
Christian Nienberg, Anika Retterath, Kira-Sophie Becher, Thorsten Saenger, Henning D. Mootz, Joachim Jose   +5 more
doaj   +1 more source

Between Condemnation and Restoration. The Idea and Practices of Restorative Justice in the Context of the Rehabilitation of Offenders

Journal of Modern Science, 2022
Objectives The aim of this paper is to outline the specifics and meaning of the idea of restorative justice in the context of dealing with offenders, as well as the approach to crime, including its genesis, forms, and methods. Another important aspect is
Dawid Kamil Wieczorek
doaj   +1 more source

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin, Usanarat Anurathapan, Rawiwan Roongpraiwan, Potchanee Dandamrongrak, Siriporn Nakhonchai, Pawin Numthavaj, Vilawan Chirdkiatgumchai   +6 more
wiley   +1 more source

Legal aspects of development of organic agriculture in Ukraine in the context of European integration [PDF]

Ekonomika Poljoprivrede (1979), 2020
In modern economic conditions, organic production is gaining global significance, partly addressing food security and contributing to the well-being of the population. Ukraine is in the top-20 of world leaders in the organic movement. In this regard, the
Ignatenko Iryna
doaj  

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Visual Active Learning for Labeling: A Case for Soundscape Ecology Data

Information, 2021
Labeling of samples is a recurrent and time-consuming task in data analysis and machine learning and yet generally overlooked in terms of visual analytics approaches to improve the process.
Liz Huancapaza Hilasaca, Milton Cezar Ribeiro, Rosane Minghim   +2 more
doaj   +1 more source

Nephrogenic Rests/Nephroblastomatosis in Patients With Unilateral Wilms Tumor Are Not Associated With an Increased Risk of Relapse: An Analysis of Patients Treated on the SIOP‐WT‐2001 Protocol in the SIOP‐UK‐CCLG and SIOP‐GPOH Studies (2001–2022)

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić, Rhoikos Furtwängler, Tanzina Chowdhury, Christian Vokuhl, Jenny Wegert, Norbert Graf   +5 more
wiley   +1 more source

Magnetoencephalography Atlas Viewer for Dipole Localization and Viewing

Journal of Imaging
Magnetoencephalography (MEG) is a noninvasive neuroimaging technique widely recognized for epilepsy and tumor mapping. MEG clinical reporting requires a multidisciplinary team, including expert input regarding each dipole’s anatomic localization.
N.C.d. Fonseca, Jason Bowerman, Pegah Askari, Amy L. Proskovec, Fabricio Stewan Feltrin, Daniel Veltkamp, Heather Early, Ben C. Wagner, Elizabeth M. Davenport, Joseph A. Maldjian   +9 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source