Representation learning of drug and disease terms for drug repositioning
Drug repositioning (DR) refers to identification of novel indications for the approved drugs. The requirement of huge investment of time as well as money and risk of failure in clinical trials have led to surge in interest in drug repositioning.
Anand, Ashish, Manchanda, Sahil
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Lupus nephritis management guidelines compared [PDF]
In the past years, many (randomized) trials have been performed comparing the treatment strategies for lupus nephritis. In 2012, these data were incorporated in six different guidelines for treating lupus nephritis.
Bajema, IM +7 more
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Crystallization of apotransferrin derivatives with small chiral molecules [PDF]
Transferin je protein krvne plazme koji se nalazi u skoro svim živim bićima i njegove su glavne funkcije transport i reguliranje količine željeza u krvi. Apotransferin je slobodan oblik proteina, onaj na koji nije vezano željezo.
Domin, Tea
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A small molecule agonist of EphA2 receptor tyrosine kinase inhibits tumor cell migration in vitro and prostate cancer metastasis in vivo [PDF]
10.1371/journal.pone.0042120PLoS ...
Aaron Petty +15 more
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Current best practice in the management of hypertensive disorders in pregnancy. [PDF]
Preeclampsia is a potentially serious complication of pregnancy with increasing significance worldwide. Preeclampsia is the cause of 9%-26% of global maternal mortality and a significant proportion of preterm delivery, and maternal and neonatal morbidity.
Khalil, A, O'Brien, P, Townsend, R
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Use of labetalol vs nifedipine in preeclampsia
Background: Pre-eclampsia is a generalized vasoconstriction state associated with vascular epithelial dysfunction rather than the vasodilation characteristic of pregnancy, characterized by proteinuric hypertension from the 20th week of pregnancy ...
Wardy Castillo López +3 more
doaj
Inadvertent intrathecal injection of labetalol
Labetalol is a combined α and β adrenergic receptor blocker. It is used to treat hypertension, especially in pregnant patients. We report a case of a female patient who was given labetalol intrathecally in place of bupivacaine due to a similar appearance
S Verma, P K Bhatia, V Sharma, P Sethi
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Doença hipertensiva na gestação: avaliação e classificação de 53 casos. [PDF]
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Silveira, Emerson da
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Mechanisms of hypertension during and after orthotopic liver transplantation in children [PDF]
The aim of this study was to assess the hormonal alterations that may mediate the systemic hypertension that develops in patients during the perioperative period of orthotopic liver transplantation.
Akerstedt +72 more
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Blood pressure management in acute stroke [PDF]
Blood pressure (BP) is elevated in 75% or more of patients with acute stroke and is associated with poor outcomes. Whether to modulate BP in acute stroke has long been debated.
Appleton, Jason P. +2 more
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