Results 71 to 80 of about 804,492 (282)

The health significance of heterotrophic bacteria in drinking water [PDF]

open access: yes, 1997
Tap water is not sterile; it contains organisms which grow in water distribution systems or inside taps and their fittings. The absence of known pathogenic bacteria is assured by the absence of the indicator organisms but concerns have been raised in the
Lightfoot, N.
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Laboratory Diagnosis of Nosocomial Bacterial Infections Using Standard Methods

open access: yesMedical Laboratory Journal, 2016
Background and objective: Implementation of standard methods for accurate detection of bacteria, correct antibiotic susceptibility testing and effective treatment of bacterial infections play important roles in development of public health and prevention
Saeideh Sadat Shobeiri   +4 more
doaj  

Lean Methodology for Pathology Laboratories: A Case Study from a Public Hospital

open access: yesTürk Patoloji Dergisi, 2019
Objective: The increase in the financial imposition of laboratories together with developing technology and evidence-based medicine applications increased the importance of quality and efficiency studies in laboratories.
Fatih DURUR, Yasemin AKBULUT
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Indagine nazionale sulle metodiche per emocoltura in Italia

open access: yesMicrobiologia Medica, 2004
Sepsis is an important cause of morbidity and mortality; Blood cultures are the standard for identifying the responsible pathogen, bacteria or fungi.A number of factors influence the yield of blood culture, most of them concerning the microbiolist skill ...
Antonio Goglio, Pierluigi Nicoletti
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1966
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1007/thumbnail ...

core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Geographical access to medical laboratory services in Shiraz, Hamadan and Shushtar: a GIS-based study

open access: yesPayesh, 2017
Objective (s): Equity in distribution of health services is one of the goals of health policy makers. Thus, an study entitled “modeling geographical access to medical laboratory services in Iran” was conducted in 2014. The present article is a case study
Jila Sadighi   +10 more
doaj  

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