Results 91 to 100 of about 2,998,255 (323)
Investigation of the Status of Laboratory Tests Conducted during Aviation Medical Examination
Hanggong uju uihakoeji, 2022 Purpose: The medical certification for pilots is required by the aviation safety authority based with the aviation safety act. Methods: In this study, medical examination items of the year of 2021 performed during the aviation medical examination in ...
JoungSoon Jang +3 more
doaj +1 more source
Muon-Induced Background Study for Underground Laboratories
, 2005 We provide a comprehensive study of the cosmic-ray muon flux and induced activity as a function of overburden along with a convenient parameterization of the salient fluxes and differential distributions for a suite of underground laboratories ranging in
A. Fassó +21 more
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Laboratory Focus on Improving the Culture of Biosafety: Statewide Risk Assessment of Clinical Laboratories That Process Specimens for Microbiologic Analysis [PDF]
, 2018 The Wisconsin State Laboratory of Hygiene challenged Wisconsin laboratories to examine their biosafety practices and improve their culture of biosafety.
Batemman, Allen C. +13 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Digital Studies, 2016 This chapter extends from research on the genealogies of modernist laboratories (aesthetic, scientific, and corporate) and their relationship to the formation of contemporary digital-humanities and new-media laboratories and collaboratories.
Dean Irvine
doaj +1 more source
On cosmology in the laboratory [PDF]
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2015 In transformation optics, ideas from general relativity have been put to practical use for engineering problems. This article asks the question how this debt can be repaid. In discussing a series of recent laboratory experiments, it shows how insights from wave phenomena shed light on the quantum physics of the event horizon.
openaire +3 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source