Results 141 to 150 of about 5,416,068 (411)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Quantum Solution of Coordination Problems [PDF]

We present a quantum solution to coordination problems that can be implemented with present technologies. It provides an alternative to existing approaches, which rely on explicit communication, prior commitment or trusted third parties.
Bernardo A. Huberman, Tad Hogg HP Laboratories   +1 more
core  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

The Cascades Proposal for the Deep Underground Science and Engineering Laboratory [PDF]

arXiv, 2007
One of the options for creating a Deep Underground Science and Engineering Laboratory (DUSEL) is a site in the Mt. Stuart batholith, a granodiorite and tonalite rock mass in the Cascade mountain range in Washington State. The batholith's 100-year history in hard-rock tunneling includes the construction of the longest and deepest tunnels in the U.S ...
arxiv  

The Costs and Benefits of Forensics [PDF]

, 2020
Supreme Court Justice Louis Brandeis famously wrote that states can be laboratories for experimentation in law and policy. Disappointingly, however, the actual laboratories that states and local governments run are not a home for experimentation.
Garrett, Brandon L.
core   +3 more sources

A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories

Journal of Medical Genetics, 2014
Background The GGGGCC-repeat expansion in C9orf72 is the most frequent mutation found in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Most of the studies on C9orf72 have relied on repeat-primed PCR (RP-PCR) methods
C. Akimoto, A. Volk, M. van Blitterswijk, M. Van den Broeck, C. Leblond, S. Lumbroso, W. Camu, B. Neitzel, O. Onodera, W. van Rheenen, S. Pinto, Markus Weber, Bradley N. Smith, M. Proven, K. Talbot, Pamela J. Keagle, A. Chesi, A. Ratti, J. van der Zee, Helena Alstermark, A. Birve, D. Calini, Angelica Nordin, Daniela C Tradowsky, W. Just, H. Daoud, Sabrina Angerbauer, M. Dejesus‐Hernandez, T. Konno, Anjali Lloyd-Jani, M. de Carvalho, K. Mouzat, J. Landers, J. Veldink, V. Silani, A. Gitler, C. Shaw, G. Rouleau, L. H. van den Berg, C. van Broeckhoven, R. Rademakers, P. Andersen, C. Kubisch   +42 more
semanticscholar   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Worksheet design to develop audio and video English activities

PODIUM, 2017
This research explores the permanent reality that is experienced in the teaching process of English modules at the Milagro State University. Students demand properly equipped laboratones and worksheets incorporating a variety of engaging activities ...
Jacqueline Maridueña Macancela, Brigita Ledesma Acosta, Miguel Astudillo Quiñonez   +2 more
doaj  

Machine learning bridging battery field data and laboratory data [PDF]

arXiv
Aiming at the dilemma that most laboratory data-driven diagnostic and prognostic methods cannot be applied to field batteries in passenger cars and energy storage systems, this paper proposes a method to bridge field data and laboratory data using machine learning.
arxiv  

Recreating Fundamental Effects in the Laboratory? [PDF]

Adv.Sci.Lett.2:121,2009, 2010
This article provides a brief (non-exhaustive) overview of some possibilities for recreating fundamental effects which are relevant for black holes (and other gravitational scenarios) in the laboratory. Via suitable condensed matter analogues and other laboratory systems, it might be possible to model the Penrose process (superradiant scattering), the ...
arxiv