Results 141 to 150 of about 5,568,953 (372)

Inside the Construction Operating Theater at SECCM Labs [PDF]

, 2018
Shawmut Design & Construction welcomes students on-site to observe and dissect the construction process as the new laboratories building takes ...
Rodrigues, Jill, Wilder, Justin
core   +1 more source

Low positivity rate and high percentage of nondermatophyte molds in an analysis of 35,257 fungal nail culture results from a United States national commercial laboratory, 2019-2022

JAAD International, 2023
Kaitlin Benedict, MPH, Shari R. Lipner, MD, PhD, Shawn R. Lockhart, PhD, Jeremy A.W. Gold, MD   +3 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Safety and Health Status of Educational and Research Laboratories of Shiraz University of Medical Sciences based on ELMERI Approach

بهداشت کار و ارتقای سلامت, 2019
Introduction: Observation of the safety principles in educational and research laboratories is very important to protect the researchers and students. This study was conducted to investigate the safety and health status of the educational and research ...
Mahdi Malakoutikhah, Hadise Korouni, Mehdi Jahangiri   +2 more
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The transformation of solid atmospheric particles into liquid droplets through heterogeneous chemistry: Laboratory insights into the processing of calcium containing mineral dust aerosol in the troposphere [PDF]

, 2003
B. J. Krueger, Vicki H. Grassian, Alexander Laskin, James P. Cowin   +3 more
openalex   +1 more source

Direct Detection Constraints on Dark Photons with the CDEX-10 Experiment at the China Jinping Underground Laboratory [PDF]

, 2020
Z. She, Lingpu Jia, Qian Yue, Hao Ma, K. Kang, Y. J. Li, M. Ağartıoğlu, Haipeng An, Jianping Chang, C. H. Cheng, Y. H. Chen, Jianping Cheng, W. H. Dai, Z. Deng, X. P. Geng, Hao Gong, Peijun Gu, Q. J. Guo, X. Y. Guo, Long He, S. M. He, H. T. He, J. Hu, T. C. Huang, Han‐Xiong Huang, H. B. Li, H. Li, Junzhen Li, J. Li, M. X. Li, X. Li, X. Q. Li, Yan Li, Bin Liao, F. K. Lin, S. T. Lin, S. K. Liu, Y. D. Liu, Y. Y. Liu, Z. Z. Liu, Y. C. Mao, Q. Y. Nie, J. H. Ning, H. Pan, Ningchun Qi, Chen-Kai Qiao, J. Ren, Xichao Ruan, B. Sevda, C. S. Shang, V. Sharma, L. Singh, M. K. Singh, T. X. Sun, C. J. Tang, W. Y. Tang, Y. Tian, G. F. Wang, L. Wang, Qing Wang, Y. Wang, Y. X. Wang, Zhimin Wang, H. T. Wong, Yongcheng Wu, Haoyang Xing, Y. Xu, Tao Xue, Y. L. Yan, L. T. Yang, Yi Nan, C. X. Yu, H. J. Yu, J. F. Yue, M. Zeng, Zhi Zeng, B. T. Zhang, L. Zhang, F. S. Zhang, Z. Y. Zhang, M. G. Zhao, J. F. Zhou, Z. Y. Zhou, J. J. Zhu   +83 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

A prospective study of the prevalence of undiagnosed coeliac disease in laboratory defined iron and folate deficiency [PDF]

, 2002
M R Howard
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source