Results 161 to 170 of about 1,629,755 (308)

Evaluation and additional recommendations for preparing a whole blood control material

open access: yesRevista de Saúde Pública
OBJECTIVE: The assessment of an easy to prepare and low cost control material for Hematology, available for manual and automated methods. MATERIAL AND METHOD: Aliquots of stabilized whole blood were prepared by partial fixation with aldehydes; the ...
Nilda E. Fink   +4 more
doaj  

Results From the Third and Fourth WHO External Quality Assessments for the Molecular Detection of Respiratory Syncytial Virus. [PDF]

open access: yesInfluenza Other Respir Viruses
do Couto Motta F   +11 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

LABORATORY

open access: yesAmerican Journal of Public Health and the Nations Health, 1928
C C, Young, M, Oglesby, H J, Knapp
openaire   +3 more sources

The organization, purpose and methods of Underwriters' Laboratories.

open access: yes, 1917
Mode of access ...
Underwriters' Laboratories.
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

CAR

open access: yes
This, the fifteenth edition of the ConsoHdated Annual Report (CAR), provides quantita- tive information about laboratory personnel, expenditures, source of funds and services identified in fifteen workload areas.

core   +1 more source

Improving public health laboratory preparedness at European Union level: learning points from experiences during the COVID-19 pandemic. [PDF]

open access: yesEuro Surveill
Parkinson S   +7 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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