Results 181 to 190 of about 1,374,270 (261)

Results From the Third and Fourth WHO External Quality Assessments for the Molecular Detection of Respiratory Syncytial Virus. [PDF]

Influenza Other Respir Viruses
do Couto Motta F, Kenji O, Barr I, Bi S, von Gottberg A, Heraud JM, Hirve S, Rughooputh S, Wolter N, Zambon M, Williams TC, Zhang W.   +11 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Charting the Future of Canadian Adult Acute Myeloid Leukemia (AML) Laboratory Testing: A Canadian Leukemia Study Group Current State Mapping of Diagnostic AML Laboratory Practice. [PDF]

Curr Oncol
Luo TYX, Usta S, McGinnis E, Mather CA, Bergeron J, Gillan T, Mahe E, Capo-Chichi JM, Berardi P, Park PC, Itani D, Rajput A, Chin-Yee B, Han FY, Butcher DT, Fesser J, DeCoteau J, Quest G, McCready E, Tsui H.   +19 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Metagenomic-driven predictive biosafety and contamination traceability in stem cell manufacturing: Translating outbreak genomics into regenerative medicine. [PDF]

Regen Ther
Elmaghrabi MM, Alghofaili SA, Mahmoud MM, ElKharashy AK, Kulsum SN.   +4 more
europepmc   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Generating Actionable Data From Antimicrobial Resistance Surveillance: Insights From the Fleming Fund's International Experience. [PDF]

Clin Infect Dis
Gupta-Wright A, Adeleke SY, Adetunji V, Ahsan Q, Amatya R, Amos B, Asare B, Bangura SIO, Buhler C, Feasey N, Gordon NC, Hopkins H, Kitutu FE, Leslie T, Lo I, Lo S, Majekodunmi A, Maudling R, Mudenda NB, Musyoki VM, Nanjebe D, Oakley T, Pathak M, Roberts T, Shehata L, Shorten T, Siddiky NA, Stelling J, Taimoor M, Thwe MS, Ting S, Torumkuney D, Turner P, Wildfire J, Worth TD.   +34 more
europepmc   +1 more source