Results 181 to 190 of about 1,629,755 (308)

Automated Laboratory Security Tiers: a framework for evaluating and mitigating biosecurity risks from latent capabilities. [PDF]

Front Microbiol
Smith MD, Hanke MS, Moritz RL, Gillum DR, Pannu J.   +4 more
europepmc   +1 more source

Artificial Laboratories.

AI Mag., 1989
An artificial laboratory is a hypothetical computing environment of the future that would integrate mathematical and statistical tools with AI methods to assist in computer modeling and simulation. An integrated approach of this kind has great potential for accelerating the rate of scientific discovery.
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Lives of a Cell: 40 Years Later, A Third Interpretation

Emerging Infectious Diseases, 2015
Virginia M. Dato
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Assessing laboratory performance for markers of kidney injury/function: a retrospective study based on External Quality Assessment. [PDF]

J Bras Nefrol
Poloni JAT, Vieira A, Lopes RM, Jerônimo D, Santos B, Meinerz G, Andriolo A.   +6 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The CDC/APHL next generation sequencing quality initiative: practical guidance to implementing quality management systems in laboratories performing next generation sequencing (phase 2). [PDF]

J Clin Microbiol
Cherney B, Diaz A, Ghattas C, Gregory M, Stow E, Onyewuenyi J, Kocherlakota LS, White L, Vidyaprakash E, Scott S, Lamar JK, McKinney G, Parekh U, Arambula D, Stang H, CDC/APHL NGS Quality Initiative.   +15 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

A national survey on laboratory practices for specimen processing, streptococcus pneumoniae identification and antimicrobial susceptibility testing in CARSS Hospitals in China. [PDF]

PLoS One
Jian C, Wang X, Yan S, Xu C.
europepmc   +1 more source