Risk-based redesign of internal quality control procedures for emergency immunoassays in clinical laboratories: a multicenter study from China. [PDF]
Xiao G +6 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A Small-Scale Regional External Quality Assessment of Nucleic Acid Amplification Tests for Bordetella pertussis in China. [PDF]
Guo Y +6 more
europepmc +1 more source
Laboratory Questionnaire; The Laboratory [PDF]
openaire +1 more source
How do Public Laboratories Collaborate with Industry? New Survey Evidence from France. [PDF]
This paper uses a survey of 130 public laboratories in France to investigate collaborative activities of laboratories with industry. Our statistical analysis shows that knowledge and technology development and transfer occurs most frequently through ...
Goddard, John Gabriel, Isabelle, Marc
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Performance of carbapenemase screening algorithms for detection of OXA-244-producing <i>Escherichia coli</i>. [PDF]
Keizer KN +9 more
europepmc +1 more source
Environment Restoration Operations Consolidated Quarterly Report - July 2015
62 pagesEnvironmental Restoration Operations Consolidated Quarterly Report, July 2015 for the Department of Energy, National Nuclear Security Administration, Sandia National Laboratories that addresses all quarterly reporting (January through March 2015)
Sandia National Laboratories/NM
core
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source

