Results 201 to 210 of about 4,260,168 (338)

Lyme disease testing by large commercial laboratories in the United States.

Clinical Infectious Diseases, 2014
A. Hinckley, N. Connally, J. Meek, Barbara J. B. Johnson, M. Kemperman, K. Feldman, Jennifer L. White, P. Mead   +7 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Characterisation of a stable laboratory co-culture of acidophilic nanoorganisms [PDF]

, 2017
Susanne Krause, Andreas Bremges, Philipp C. Münch, Alice C. McHardy, Johannes Gescher   +4 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Building capacities in Sub-Saharan African countries for antimicrobial resistance surveillance in the food and agriculture sectors using the FAO ATLASS tool. [PDF]

Front Vet Sci
Ouoba LII, Treilles M, Noumedem RNG, Keck N, Kiptiness JK, Diallo AA, Mouillé B, Gourlaouen M, Kimani T, Obonyo M, Niang M, Dsani E, Latronico F, Garcia AD, Kabali E, Song J, Shamsuddin M.   +16 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Persistent ANCA Positivity in <i>Granulicatella adiacens</i>-associated Endocarditis: Diagnostic Implications of Methodological Variability. [PDF]

Kidney Int Rep
Linse V, De Groot K, Wiech T, Sachs UJ, Hellmich B, Husain-Syed F.   +5 more
europepmc   +1 more source

Development of an Exploratory Simulation Tool: Using Predictive Decision Trees to Model Chemical Exposure Risks and Asthma-like Symptoms in Professional Cleaning Staff in Laboratory Environments [PDF]

Hayden D. Hedman
openalex   +1 more source

Urban Laboratories: Experiments in Reworking Cities

, 2014
A. Karvonen, B. Heur
semanticscholar   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source