Specialism, the Laboratory, and Practical Medicine [PDF]
K. C. SHATTUCK
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Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
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How do Public Laboratories Collaborate with Industry? New Survey Evidence from France. [PDF]
This paper uses a survey of 130 public laboratories in France to investigate collaborative activities of laboratories with industry. Our statistical analysis shows that knowledge and technology development and transfer occurs most frequently through ...
Goddard, John Gabriel, Isabelle, Marc
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Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
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XIV.—Notes from the Gatty Marine Laboratory, St. Andrews.—No. XVIII. [PDF]
M'Intosh
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Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
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The Wing Veins of Insects . By Professor C. W. Woodworth. University of California Publications, Technical Bulletins, College of Agriculture, Agricultural Experiment Station. Entomology, Vol. I., No. 1, pp. 1-152, September, 1906. Contributions from the Zoological Laboratory of the Museum of Comparative Zoology at Harvard College, under the direction of B. L. Mark. No. 181. [PDF]
James G. Needham
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