This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian+10 more
wiley +1 more source
Whole genome mutagenicity evaluation using Hawk-Seq™ demonstrates high inter-laboratory reproducibility and concordance with the transgenic rodent gene mutation assay. [PDF]
Matsumura S+16 more
europepmc +1 more source
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová+14 more
wiley +1 more source
The variability of in vivo sunscreen sun protection factor values. [PDF]
Cole C, Colson B, Uhlig S.
europepmc +1 more source
XIII.—Notes from the Chemical Laboratory of the Yorkshire College. No. I. Reduction of potassium dichromate by oxalic acid [PDF]
C. H. Bothamley
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YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy+9 more
wiley +1 more source
Optimal Timing for Expanding Diagnostic Laboratories, South Korea. [PDF]
Park JS, Kim GJ, Lee SW.
europepmc +1 more source
THE NEED OF MEDICAL COOPERATION IN LABORATORY WORK.ADDRESS OF CHAIRMAN OF THE SECTION ON PATHOLOGY AND PHYSIOLOGY, AT THE FIFTY-EIGHTH ANNUAL SESSION OF THE AMERICAN MEDICAL ASSOCIATION AT ATLANTIC CITY, JUNE, 1907. [PDF]
Walter L. Bierring
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Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster+3 more
wiley +1 more source