A Laboratory Manual of Organic Chemistry for Medical Students. [PDF]
M. Abigail Steel
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TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
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Hanford Laboratories operation monthly activities report, November 1958
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XIII.—Notes from the Chemical Laboratory of the Yorkshire College. No. I. Reduction of potassium dichromate by oxalic acid [PDF]
C. H. Bothamley
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Perceptions of psychological safety in high-containment laboratories: mixed method survey of community members and industry experts. [PDF]
Sargent M+8 more
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The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
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THE NEED OF MEDICAL COOPERATION IN LABORATORY WORK.ADDRESS OF CHAIRMAN OF THE SECTION ON PATHOLOGY AND PHYSIOLOGY, AT THE FIFTY-EIGHTH ANNUAL SESSION OF THE AMERICAN MEDICAL ASSOCIATION AT ATLANTIC CITY, JUNE, 1907. [PDF]
Walter L. Bierring
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External quality assessment for molecular detection of sand fly-borne phleboviruses circulating in the Mediterranean Basin. [PDF]
Ayhan N+6 more
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
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