Results 51 to 60 of about 5,568,953 (372)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

European underground laboratories: An overview

open access: yes, 2005
Underground laboratories are complementary to those where the research in fundamental physics is made using accelerators. This report focus on the logistic and on the background features of the most relevant laboratories in Europe, stressing also on the ...
Miramonti, Lino
core   +2 more sources

Standardization and application of microsatellite markers for variety identification in tomato and wheat [PDF]

open access: yes, 2001
The present study is part of a EU project that aims to demonstrate the technical viability of STMS markers for variety identification. As examples two important European crop species, tomato and wheat were chosen. Initially, about 30-40 STMS markers were
Bredemeijer, G.   +5 more
core   +2 more sources

34th Malaysian Association of Clinical Biochemists Annual Conference in collaboration with 2nd Malaysian Biomedical Science Association Symposium 2024

open access: yesLife Sciences, Medicine and Biomedicine
The Malaysian Association of Clinical Biochemists (MACB) and the Malaysian Biomedical Science Association (MyBiomed) successfully organized the 34th MACB Conference in conjunction with the 2nd MyBiomed Symposium 2024.
Wan Amir Nizam Wan Ahmad   +10 more
doaj   +1 more source

Reporting on 16 years of laboratory capacity building while exploring the future of WOAH's Laboratory Twinning Programme

open access: yesFrontiers in Veterinary Science, 2022
Animal health laboratories are an increasingly important part of safeguarding animal and public health due to their role in surveillance and diagnostics of animal diseases, food safety, and in the development and production of medicinal products ...
Mariana Marrana   +6 more
doaj   +1 more source

Global Availability of Antivenoms: The Relevance of Public Manufacturing Laboratories

open access: yesToxins, 2018
Snakebite envenoming is a serious global public health problem, and international initiatives, under the coordination of the World Health Organization and its regional offices, are being developed to reduce the impact of this neglected tropical disease ...
J. Gutiérrez
semanticscholar   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Emerging Infections Program—State Health Department Perspective

open access: yesEmerging Infectious Diseases, 2015
The Emerging Infections Program (EIP) is a collaboration between the Centers for Disease Control and Prevention and 10 state health departments working with academic partners to conduct active population-based surveillance and special studies for several
James L. Hadler   +9 more
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

From Science to Design: the Design4Materials virtuous cycle [PDF]

open access: yes, 2017
Despite the large number of innovative materials developed in laboratories worldwide, their application in new mass-produced products is complicated.
Carullo, Rossana   +4 more
core   +2 more sources

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