Results 61 to 70 of about 2,962,077 (341)
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Monitoring of environmental aspects and impacts in research/educational laboratories
Payesh, 2008 Objective(s): The purpose of this study was to determine the types of waste produced by the research laboratories of the Department of Environmental Engineering at Tehran University of Medical Sciences and to assess the environmental impact of these ...
Nouri J. +3 more
doaj
Nuclei as Laboratories: Nuclear Tests of Fundamental Symmetries [PDF]
, 2006 The prospect of a rare isosotope accelerator facility opens up possibilities for a new generation of nuclear tests of fundamental symmetries. In this talk, I survey the current landscape of such tests and discuss future opportunities that a new facility ...
Ramsey-Musolf, Michael J.
core +2 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Near-peer Teaching in Histology Laboratory
International Journal of Medical Students, 2016 Background: Near-peer teaching is an educational method based on being taught by one or more students who are more advanced in one specific area of the same curriculum. The aim of this study was to analyze outcomes and medical students’ reactions to near-
María de los Ángeles Cambrón-Carmona +8 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Laboratory diagnostics performance in Uganda: A survey of test availability and constraints
Journal of Interventional Epidemiology and Public HealthIntroduction: Clinical laboratory services are a critical component of the health system for effective disease diagnosis, treatment, control and prevention. However, many laboratories in Sub-Saharan Africa remain dysfunctional.
Noel Namuhani +5 more
doaj +1 more source