Results 81 to 90 of about 5,568,953 (372)

Gene Therapy for Inherited Retinal Diseases: From Laboratory Bench to Patient Bedside and Beyond [PDF]

open access: gold, 2023
Anand Singh Brar   +7 more
openalex   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Simulating Interference and Diffraction in Instructional Laboratories

open access: yes, 2012
Studies have shown that standard lectures and instructional laboratory experiments are not effective at teaching interference and diffraction. In response, the author created an interactive computer program that simulates interference and diffraction ...
Maurer, Leon
core   +1 more source

Computer‐based learning in psychology using interactive laboratories [PDF]

open access: yes, 1994
Traditional approaches to computer‐based learning often focus on the delivery of information. Such applications usually provide large stores of information which can be accessed in a wide variety of ways.
Richards, Stephen
core   +3 more sources

WHO public health laboratories webinar series – an online platform to disseminate testing recommendations and best practices during health emergencies

open access: yesFrontiers in Public Health
Laboratories play a central role in managing public health emergencies. The COVID-19 pandemic imposed unique challenges on global laboratory systems, including testing protocol uncertainties, supply shortages, rapid need for information dissemination ...
Céline Barnadas   +6 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Laboratory Focus on Improving the Culture of Biosafety: Statewide Risk Assessment of Clinical Laboratories That Process Specimens for Microbiologic Analysis [PDF]

open access: yes, 2018
The Wisconsin State Laboratory of Hygiene challenged Wisconsin laboratories to examine their biosafety practices and improve their culture of biosafety.
Batemman, Allen C.   +13 more
core   +1 more source

Muon-Induced Background Study for Underground Laboratories

open access: yes, 2005
We provide a comprehensive study of the cosmic-ray muon flux and induced activity as a function of overburden along with a convenient parameterization of the salient fluxes and differential distributions for a suite of underground laboratories ranging in
A. Fassó   +21 more
core   +1 more source

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