Results 81 to 90 of about 4,260,168 (338)

The Impact of Different DNA Extraction Kits and Laboratories upon the Assessment of Human Gut Microbiota Composition by 16S rRNA Gene Sequencing

PLoS ONE, 2014
Introduction Determining bacterial community structure in fecal samples through DNA sequencing is an important facet of intestinal health research. The impact of different commercially available DNA extraction kits upon bacterial community structures has
N. Kennedy, A. Walker, S. Berry, S. Duncan, F. Farquarson, P. Louis, J. Thomson, T CA JC H C A C P M CA JC JC CG C WG NJ A P K K DC Ahmad Anderson Barrett Drummond Edwards Hart Hawke, T. Ahmad, CA Anderson, JC Barrett, H. Drummond, C. Edwards, A. Hart, C. Hawkey, P. Henderson, M. Khan, C. Lamb, JC Lee, J. Mansfield, C. Mathew, C. Mowat, WG Newman, N. Prescott, A. Simmons, P. Simpson, K. Taylor, K. Taylor, D. Wilson, J. Satsangi, H. Flint, J. Parkhill, C. Lees, G. Hold   +33 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

WORKSHOPS ON QUALITY MANAGEMENT SYSTEMS FOR PROFESSIONALS FROM BIOMEDICAL RESEARCH LABORATORIES [PDF]

Revista Gestão & Saúde, 2013
This paper describes the training experience of the quality multipliers from research laboratories of a public health institution. This research presented the design and results of the workshops. The methodology used was the workshops on group dynamics
Ivanete Milagres Presot, Helena Maria Campos, Celina Maria Modena   +2 more
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Measuring Operational Efficiency of Highly Specialised Clinical Laboratories at a University Teaching Hospital– A DEA Approach

Online Journal of Health & Allied Sciences, 2020
Purpose: Evaluation of the efficiencies of clinical laboratories is a must for the laboratory and hospital managers. It facilitates an understanding of the current situation of the ongoing processes and allows for targeted measures.
Vidya Jha, Dinesh TA, Abhijath V, Prem Nair   +3 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Inflammatory markers are beneficial in the early stages of cerebral venous thrombosis

Arquivos de Neuro-Psiquiatria
Cerebral vein thrombosis (CVT) is a rare but serious cause of acute stroke. Inflammation is a hypothetical etiological factor in CVT. Objective: The aim of this study was to evaluate inflammatory marker levels in CVT patients and compare these with ...
Aysel Tekesin, Abdulkadir Tunç
doaj   +1 more source

Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature [PDF]

, 2016
Jeffrey I. Boucher, Daniel N. Bolon, Dan S. Tawfik   +2 more
openalex   +1 more source

‘Give Me a Laboratory and I Will Lower Your Carbon Footprint!’ — Urban Laboratories and the Governance of Low-Carbon Futures

, 2014
The increasing threat of climate change has created a pressing need for cities to lower their carbon footprints. Urban laboratories are emerging in numerous cities around the world as a strategy for local governments to partner with public and private ...
James Evans, A. Karvonen
semanticscholar   +1 more source