Results 81 to 90 of about 2,998,255 (323)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Inflammatory markers are beneficial in the early stages of cerebral venous thrombosis
Arquivos de Neuro-PsiquiatriaCerebral vein thrombosis (CVT) is a rare but serious cause of acute stroke. Inflammation is a hypothetical etiological factor in CVT. Objective: The aim of this study was to evaluate inflammatory marker levels in CVT patients and compare these with ...
Aysel Tekesin, Abdulkadir Tunç
doaj +1 more source
Stardust in the Laboratory [PDF]
Science, 1996 The isotopic composition of stardust, the matter created as stars burn, is a rich source of information about stellar evolution, synthesis of elements, and solar system formation. In his Perspective, Zinner reviews recent work on the laboratory analysis of stardust preserved in micrometeorites presented at the 58th Meteoritical Society Meeting.
openaire +4 more sources
Enhancing laboratory capacities in the Caribbean for better animal health regional surveillance [PDF]
, 2012 The Caribbean Animal Health Network (CaribVET) is a collaboration network of veterinary services, laboratories, research institutes and regional/international organizations in the Caribbean.
Barcos, L. +5 more
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FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Spending to Death: Wasteful Government Spending, Transparency Failures, and the Secretive World of Federal Dog Experiments [PDF]
, 2016 "The Government Accountability Office has stated, "For decades…the public has been concerned that dogs and cats used in research could be treated inhumanely…"Indeed, in 1966, the U.S.
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Shell galaxies as laboratories for testing MOND
, 2014 Tests of MOND in ellipticals are relatively rare because these galaxies often lack kinematic tracers in the regions where the MOND effects are significant.
Bartošková, Kateřina +4 more
core +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Einstein (São Paulo)OBJECTIVE: To evaluate the process of implementing a quality management system in a basic research laboratory of a public institution, particularly considering the feasibility and impacts of this improvement.
Hilda Carolina de Jesus Rios Fraga +4 more
doaj +1 more source