TOXICOLOGICAL STUDY OF MEBUDIPINE AND DIBUDINE, TWO NEW CALCIUMCHANNEL BLOCKERS, IN SACCHAROMYCES CERVISES AND ISOLATED RAT HEPATOCYTES CELLS INVITRO [PDF]
Mebudipine and Dibudipine are two new calcium antagosists used in laboratory animals. Toxicological testing were evaluated in cultured mouse cells in‐vitro and on growth yeast cells . It is shown that in these two system it is safe and no toxicological
بهلولی, شهاب +4 more
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Nomenclature for standardized designation of diploid genotypes in genetically modified laboratory animals. [PDF]
Lab Anim, 2023 Dobrowolski P, Buch T, Nagel-Riedasch S.
europepmc +1 more source
Anti-inflammatory, hypoglycemic and hypolipidemic effects of Stevia rebaudiana bertoni leaf extract in an experimental model of diabetes mellitus and obesity in laboratory animals [PDF]
, 2021 Irina I. Novikova +7 more
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Morphometrics of Xenopus laevis Kept as Laboratory Animals. [PDF]
Animals (Basel), 2022 Böswald LF +4 more
europepmc +1 more source
Heat Resistance of <I>Cladosporium</I> Isolated from Laboratory Animal Facilities
, 1990 Satoru Kawai +2 more
openalex +2 more sources
Is the risk of developing atopic sensitization and bronchial asthma in animal laboratory workers preventable in well-defined susceptible individuals? [PDF]
, 2017 Gennaro Liccardi +5 more
openalex +1 more source