Results 141 to 150 of about 5,432,956 (261)

Brookhaven National Laboratory Reports

, 1963
Report issued by the Brookhaven National Laboratory discussing high-pressured gamma loops. As stated in the introduction, "this latest endeavor involved three test cells, a gamma irradiation pool and supporting equipment, as well as an enlarged high ...
Brookhaven National Laboratory
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches. [PDF]

Animal Model Exp Med
Faraji M, Faraji M, Kazemipour N.
europepmc   +1 more source

University of California Radiation Laboratory Reports UCRL-1610

, 1951
Quarterly summary report of studies conducted through the Radiation Laboratory, University of California.
University of California. Radiation Laboratory.
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SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Comprehensive methodology for evaluating the immobility responses in laboratory animals. [PDF]

MethodsX
Estrada-Silva MA, Cruz-Rodríguez J, Silva-Luna G, Torres-Mendoza JN, Luna-Tenorio E, Luna-Viramontes NI, Vázquez-Vargas ID, Granados-Rivas B, Luna-Muñoz J, Flores G, Ramírez LG, la Cruz-López F.   +11 more
europepmc   +1 more source

Morphometrics of Xenopus laevis Kept as Laboratory Animals. [PDF]

Animals (Basel), 2022
Böswald LF, Matzek D, Mohr H, Kienzle E, Popper B.   +4 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

How University Students Evaluate the Use of Laboratory Animals: The Role of Species and Individual Differences. [PDF]

Animals (Basel)
Ruiz-Sancho L, Saez-Atxukarro O, Gomez-Gastiasoro A, Azkona G.   +3 more
europepmc   +1 more source

Sheep as a large animal model for hearing research: comparison to common laboratory animals and humans. [PDF]

Lab Anim Res, 2023
Lue PY, Oliver MH, Neeff M, Thorne PR, Suzuki-Kerr H.   +4 more
europepmc   +1 more source