Results 81 to 90 of about 2,499,429 (330)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The place of D-dimer and L-lactate levels in the early diagnosis of acute mesenteric ischemia [PDF]

open access: yes, 2015
INTRODUCTION: Acute mesenteric ischemia (AMI) is an abdominal-vascular emergency which is rare and has high mortality rates (60-80 %) due to late diagnosis (1-3).
Aydin, B.   +5 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Modeling multiple sclerosis in laboratory animals [PDF]

open access: yes, 2018
Inflammatory demyelinating disease of the central nervous system is one of the most frequent causes of neurological disability in young adults. While in situ analysis and in vitro models do shed some light onto the processes of tissue damage and cellular
Becher, Burkhard   +2 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Complete mitochondrial genome and the phylogenetic position of the Mugilogobius myxodermus: an endemic freshwater gobiid fish in China

open access: yesMitochondrial DNA. Part B. Resources, 2017
The Mugilogobius myxodermus is an endemic freshwater fish in china. Herein, we sequenced and assembled the first complete mitogenome of M. myxodermus. The total length of the mitogenome is 16,495 bp, containing 13 protein-coding genes, two ribosomal RNAs
Lei Cai, Ren Huang, Jianjun Li
doaj   +1 more source

Amphibians as Laboratory Animals [PDF]

open access: yesILAR Journal, 1995
Scientists Center for Animal Welfare (Available from SCAW, Golden Triangle Building One, 7833 Walker Drive, Suite 340, Greenbelt, MD 20770. Tel: 301/345-3500; Fax: 301/345-3503). Scott WB, Crossman EJ. 1973. Freshwater Fish of Canada. Fisheries Research Board of Canada, Bulletin 184. Snodgrass MJ, Burke JD, Meetz GD. 1976.
openaire   +2 more sources

Soil Properties and their Influence on Grassland Production under Low Input and Organic Farming Conditions [PDF]

open access: yes, 2006
End of project reportThis project set out to identify soil properties that most influence grassland production under low mineral nitrogen input conditions. Sixteen farms were selected in Counties Limerick and Clare and the soil sampled. Soil physical and
Breen, J.   +3 more
core  

Living with Transgenic Animals [PDF]

open access: yes, 2014
This article examines Farm Sanctuary’s failed effort to save the Enviropigs. In the Spring of 2012, after losing the main source of funding for its Enviropig project, the University of Guelph, in Ontario, Canada, killed the last sixteen members of this ...
Jonathan L. Clark
core   +1 more source

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