Results 41 to 50 of about 743,133 (291)

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]

, 2012
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari, Alimuddin Zumla, Armand, Axelsson-Robertson, Banada, Ben Marais, Betsou, Blakemore, Boehme, Boehme, Cattamanchi, Chow, Cuevas, Cuevas, Cuevas, Cuevas, Diel, Dowdy, Dye, European Centre for Disease Prevention and Control, Ferrara, Giovanni-Batista Migliori, Giuseppe Pantaleo, Green, Harari, Helb, Helen Cox, Hillemann, Hohn, Ibrahim Abubakar, Jeremiah Chakaya, John, Justin O’Grady, Karin Weyer, Keeler, Kemp, Kunnath-Velayudhan, Lawn, Lawn, Lawn, Lawn, Lawn, Lemaire, Lin, Ling, Liu, Long, Lucica Ditui, Lynn Zijenah, Mann, Marais, Marais, Marais, Marais, Marco Schito, Markus Maeurer, Marlowe, Martin P. Grobusch, Martina Casenghi, Matthew Bates, McNerney, Michael Hoelscher, Michel Pletschette, Minion, Moore, Morris, Mwaba, Nathan Ford, Nathanson, National Institute for Health and Clinical Excellence, Nicol, Nicol, Oberhelman, O’Grady, Peter, Peter Mwaba, Peter S. Kim, Rifat Atun, Rose, Ruth McNerney, S. Bertel Squire, Samana Schwank, Sester, Shah, Soumya Swaminathan, Squire, Squire, Steingart, Steingart, Steingart, Steve Lawn, Storla, Temple, Theron, Timothy D. Mchugh, Treatment Action Group, Tully, Vadwai, Van Rie, van Wyk, Wallis, Walzl, Weyer, Wilson, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, Wright, Wright, Zar, Ziad Memish, Zumla, Zumla   +118 more
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Problems with Bartonellosis Diagnosis

Aktualʹnaâ Infektologiâ, 2016
The article describes clinical cases of typical course of cat scratch disease, as well as its combination with Lyme borreliosis. Differentiation with other organic causes and corresponding laboratory tests enabled to establish the diagnosis and to ...
V.S. Kopcha
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Laboratory diagnostics and quality of blood collection [PDF]

Journal of Medical Biochemistry, 2015
Summary: Diagnostic blood samples collected by phlebotomy are the most common type of biological specimens drawn and sent to laboratory medicine facilities for being analyzed, thus supporting caring physicians in patient diagnosis, follow-up and/or ...
Lippi Giuseppe, Salvagno Gian Luca, Picheth Geraldo, Guidi Gian Cesare   +3 more
doaj  

Nigeria’s efforts to strengthen laboratory diagnostics – Why access to reliable and affordable diagnostics is key to building resilient laboratory systems

African Journal of Laboratory Medicine, 2020
No abstract available.
Dhamari Naidoo, Chikwe Ihekweazu
doaj   +1 more source

Susceptibility Provision Enhances Effective De-escalation (SPEED): utilizing rapid phenotypic susceptibility testing in Gram-negative bloodstream infections and its potential clinical impact [PDF]

, 2019
Objectives We evaluated the performance and time to result for pathogen identification (ID) and antimicrobial susceptibility testing (AST) of the Accelerate Pheno™ system (AXDX) compared with standard of care (SOC) methods.
Blevins, Sarah, Bocian, Brittany, Davis, Thomas E., Desai, Armisha, Emery, Christopher L., Hiles, Jon, Manaloor, John J., Schmitt, Bryan H., Schneider, Jack G., Smith, Nathan W., Wood, James B., Wrin, Justin   +11 more
core   +1 more source

Malaria in children of Tshimbulu (Western Kasai, Democratic Republic of the Congo): epidemiological data and accuracy of diagnostic assays applied in a limited resource setting [PDF]

, 2016
BACKGROUND: The literature data on malaria in Western Kasai, DRC, are limited and inadequate. A recent molecular survey there has detected Plasmodium ovale and Plasmodium malariae as mixed infections with Plasmodium falciparum.
Bellina, Livia, CANCRINI, Gabriella, Fullin, Valerio, GABRIELLI, SIMONA, Katende, Boniface Kabasele, MILARDI, GIOVANNI LUIGI, Totino, Valentina   +6 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

CONTEMPORARY DIAGNOSIS OF HEPATIC HYDATID ECHINOCOCCOSIS

Паёми Сино
This literature review summarizes the latest diagnostic methods for diagnosing hepatic cystic echinococcosis (HCE). The study involved a systematic search of bibliographic databases, including eLibrary, PubMed, and Medline, covering the period from ...
Pakhnov Dmitry Vladimirovich, Odishelashvili Givi Domentievich, Lutsky Dmitry Leonidovich, Pakhnova Liya Ruslanovna   +3 more
doaj   +1 more source