Results 101 to 110 of about 9,887,563 (334)
Dynamic behaviour and energy dissipation of offline air pockets in transient pipe flows
Engineering Applications of Computational Fluid MechanicsThe traditional one-dimensional (1D) model often fails to accurately predict the dynamic pressure response of large offline air pockets during transients, due to a lack of comprehensive understanding of the underlying mechanisms of transient interaction ...
Yun-Jie Li +6 more
doaj +1 more source
The LUNA experiment at Gran Sasso Laboratory
EPJ Web of Conferences, 2014 Accurate knowledge of thermonuclear reaction rates is a key issue in nuclear astrophysics since it is important for understanding the energy generation, neutrino production and the synthesis of the elements in stars. Cross-section measurements are mainly
Guglielmetti Alessandra
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
National pride and tax compliance: A laboratory experiment using a physiological marker. [PDF]
PLoS One, 2023 Macintyre A +3 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Image and text presentation forms in destination marketing: An eye-tracking analysis and a laboratory experiment. [PDF]
Front Psychol, 2022 Yang W +5 more
europepmc +1 more source
On the unsteady dynamics of synthetic leaves: Laboratory experiments using synchronized PIV and DIC
, 2021 Lai Wing +4 more
openalex +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Macroeconomic expectations, central bank communication, and background uncertainty: A COVID-19 laboratory experiment. [PDF]
J Econ Dyn Control, 2022 Petersen L, Rholes R.
europepmc +1 more source