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Introduction. Systemic lupus erythematosus (SLE) is one of the major medical and social problems, as it is most commonly seen in young people, accompanied by a variety of multiple organ lesions and clinical manifestations that often lead to disability ...
Guta S. +4 more
core +1 more source
Mucosal immune responses following intestinal nematode infection. [PDF]
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Harris, N. L. +9 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Laboratory diagnosis of infective endocarditis [PDF]
The diagnosis of infective endocarditis is based on positive blood cultures. Modern microbiological techniques can isolate the aetiological agent in 90-95% of cases. The rapidity of detection has been improved by inoculation of 10 ml of blood, adequate dilution and media and systematic subcultures.
openaire +2 more sources
Introduction: Clonorchis sinensis is one of the most important foodborne pathogens in humans, and can cause biliary diseases such as gallstones, cholecystitis, cholangitis, and cholangiocarcinoma.
Chao Yan +10 more
doaj +1 more source
Background Shigella is a Gram-negative facultative intracellular bacterium that causes bacillary dysentery in humans. Shigella invades cells of the colonic mucosa owing to its virulence plasmid-encoded Type 3 Secretion System (T3SS), and multiplies in ...
Ramón Cervantes-Rivera +2 more
doaj +1 more source
Hanta Virus Infection During Dengue Virus Infection Outbreak in Indonesia [PDF]
Aim: to investigate which recent infection could have caused the present dengue-like symptoms, in adult patients clinically fulfilling the WHO criteria for dengue, in which serologically were not confirmed for dengue virus infections.
Hadisaputro, Suharyo +7 more
core
Host-pathogen interactions in Campylobacter infections: the host perspective
Campylobacter is a major cause of acute bacterial diarrhea in humans worldwide. This study was aimed at summarizing the current understanding of host mechanisms involved in the defense against Campylobacter by evaluating data available from three sources:
Dep Infectieziekten Immunologie +18 more
core +1 more source
The natural history of trachoma infection and disease in a Gambian cohort with frequent follow-up. [PDF]
BACKGROUND: The natural history of ocular Chlamydia trachomatis infections in endemic communities has not been well characterised and is an important determinant of the effectiveness of different mass treatment strategies to prevent blindness due to ...
Nicholas C Grassly +14 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

