Results 131 to 140 of about 8,036,410 (300)

Advances in laboratory diagnosis of neonatal hyperbilirubinemia and peculiarities in plateau regions: a review of evidence

Frontiers in Pediatrics
High-altitude neonatal hyperbilirubinemia refers to a common condition in newborns residing at elevations of 2,500 meters or higher. This condition arises from the combination of high-altitude environmental factors—such as hypoxia and low atmospheric ...
Changqing Tang, Changqing Tang, Lijun Xia, Lijun Xia, Dengbo Xu, Dengbo Xu   +5 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Laboratory Medicine

BioMed Research International, 2013
Hur, Mina, John, Andrew St., La Gioia, Antonio   +2 more
openaire   +2 more sources

Laboratory medicine : a national status report [PDF]

Although the U.S. ranks highest in per capita health care spending, there is overwhelming evidence of gaps between well-founded standards of care and health care practice. The Institute of Medicine reports, To Err is Human: Building a Safer Health System

core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Uso irracional de las pruebas de laboratorio clínico por parte de los médicos de asistencia

Medisan
Introducción: las pruebas diagnósticas son herramientas de ayuda para la decisión clínica, de manera que su uso se considera inapropiado cuando aportan información escasa o nula para tal decisión. La medicina de laboratorio basada en la evidencia combina
Cira Cecilia León Ramentol, Guillermo Rivero Fexas, Mavel López Machado, Isis Patricia Rodríguez Socarrás   +3 more
doaj  

Establishing denominator-consistent Six Sigma benchmarks for venous blood specimen rejection: a multi-center retrospective quality-indicator study using 21 million specimens in Western China

Frontiers in Medicine
BackgroundPre-analytical venous blood specimen rejection can delay clinical decision-making and may increase laboratory workload, yet multicenter benchmarking remains limited by inconsistent rejection definitions and denominator selection.
Chunbao Xie, Changrui Sun, Changrui Sun, Li Xiao, Tao Chen, Fengxi Jia, Fangkui Xiong, Zehong Wang, Yulian Zhou, Hengyong Yu, Huan Ding, Yifeng Huang, Xiaoting Zhan, Guangcheng Luo, Jiawei Zeng, Yi Huang   +15 more
doaj   +1 more source

Laboratory medicine

Academic Medicine, 1987
J M, McDonald, L, Jarett
openaire   +3 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Implementing laboratory quality management systems in Ghana: A quality audit of accreditation readiness in clinical and public health laboratories (2021–2023)

African Journal of Laboratory Medicine
Background: The Stepwise Laboratory Improvement Process Towards Accreditation (SLIPTA) checklist has demonstrated improvement in laboratory quality in Africa. In Ghana, however, implementation has targeted mainly higher-tier clinical laboratories.
Emma E. Kploanyi, David W. Dowdy, Joseph Kenu, Benjamin Buade, Benedicta Owusu-Arthur, David A. Opare, Franklin Asiedu-Bekoe, Alfred E. Yawson, Ernest Kenu, Lee F. Schroeder   +9 more
doaj   +1 more source