Results 111 to 120 of about 2,797,375 (301)

ЛАБОРАТОРНАЯ МЕДИЦИНА — ФУНДАМЕНТ СОВРЕМЕННОЙ ТЕРАПЕВТИЧЕСКОЙ КЛИНИКИ

Архивъ внутренней медицины, 2014
Analytical reliability and clinical significance of laboratory data allows to consider them as a basis for diagnosis and treatment monitoring in therapeutic clinic.
Л. П. Ефимова
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Harmonization Of Quality Indicators In Laboratory Medicine. A Preliminary Consensus

, 2015
Quality indicators (QIs) are fundamental tools for enabling users to quantify the quality of all operational processes by comparing it against a defined criterion.
Astion M.L., Sciacovelli L., Sumarac Z., Simundic A.-M., Barth J.H., Plebani M., Chen W., Shcolnik W., Petinos P., De Oliveira Galoro C.A., Miller W.G., Ivanov A., Escuer M.I.   +12 more
core   +1 more source

The Trend of Laboratory Medicine Based on Big Data

iLABMED
Laboratory medicine, a fundamental component of clinical medicine, is undergoing an unprecedented transformation with the emergence of the big data era.
Chengcheng Bi, Shitao Zhou, Xiaobing Zhao, Zhen Wang, Feng Tian   +4 more
doaj   +1 more source

ETHICS IN LABORATORY MEDICINE [PDF]

Indian Journal of Medical Microbiology, 2007
Arora, DR, Arora, B
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Neighboring countries: The same professional aim in development laboratory medicine [PDF]

Journal of Medical Biochemistry, 2019
During 15th Belgrade Symposium for Balkan Region (April 11 and 12, 2019, Belgrade, www.dmbj.org.rs) Society of Medical Biochemists of Serbia organized scientific and professional program with aim to discuss laboratory medicine topics of mutual interest ...
Majkić-Singh Nada
doaj  

Laboratory and Sports medicine [PDF]

Clinical Chemistry and Laboratory Medicine (CCLM), 2021
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source