Results 101 to 110 of about 8,036,410 (300)

Using the failure mode and effects analysis model to improve parathyroid hormone and adrenocorticotropic hormone testing

Risk Management and Healthcare Policy, 2016
Racheli Magnezi,1 Asaf Hemi,1 Rina Hemi2 1Department of Management, Public Health and Health Systems Management Program, Bar Ilan University, Ramat Gan, 2Endocrine Service Unit, Sheba Medical Center, Tel Aviv, Israel Background: Risk management in health
Magnezi R, Hemi A, Hemi R
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Serum Hepatocyte-Derived Fibrinogen-Related Protein-1: A Novel Biomarker for Severity and Clinical Outcome in Acute Ischemic Stroke

Journal of Inflammation Research
Fang Liang,1,* Xia Li,2,* Liangnian Wei,1,* Rong Chen,1,* Kaijing Zhang,2 Ling Wu,1 Yiting Hua,1 Wenlei Li,3 Yuan Zhu,3 Shijia Liu,4 Chunbing Zhang,1,2,5 Pengfei Li1,21Department of Clinical Laboratory, Jiangsu Province ...
Liang F, Li X, Wei L, Chen R, Zhang K, Wu L, Hua Y, Li W, Zhu Y, Liu S, Zhang C, Li P   +11 more
doaj  

ETHICS IN LABORATORY MEDICINE [PDF]

Indian Journal of Medical Microbiology, 2007
Arora, DR, Arora, B
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Impacts of the advancement in artificial intelligence on laboratory medicine in low‐ and middle‐income countries: Challenges and recommendations—A literature review

Health Science Reports
Background and Aims Artificial intelligence (AI) has emerged as a transformative force in laboratory medicine, promising significant advancements in healthcare delivery. This study explores the potential impact of AI on diagnostics and patient management
Malik Olatunde Oduoye, Eeshal Fatima, Muhammad Ali Muzammil, Tirth Dave, Hamza Irfan, F. N. U. Fariha, Andrew Marbell, Samuel Chinonso Ubechu, Godfred Yawson Scott, Emmanuel Ebuka Elebesunu   +9 more
doaj   +1 more source

Update on Patient Self-Testing with Portable and Wearable Devices: Advantages and Limitations

Diagnostics
Laboratory medicine has undergone a deep and multifaceted revolution in the course of human history, in both organizational and technical terms. Over the past century, there has been a growing recognition of the need to centralize numerous diagnostic ...
Giuseppe Lippi, Laura Pighi, Camilla Mattiuzzi   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Laboratory and Sports medicine [PDF]

Clinical Chemistry and Laboratory Medicine (CCLM), 2021
openaire   +2 more sources