Results 41 to 50 of about 2,580,346 (406)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Global Employment Trends [PDF]
, 2006 The January 2006 report documents the current trend in Global employment as well as the effects of the Asian tsunami, migration, and the oil shock in ...
International Labour Office
core +1 more source
Humanities & Social Sciences CommunicationsThis article studies educational decisions, focusing on intentions of enrolment in master’s education of STEM bachelor students. Integrating human capital theory with concepts of cultural and social capital, we propose a two-level model for the choice of
Ana-Maria Zamfir +2 more
doaj +1 more source
Employer Expectations Regarding the Competencies of Employees on the Energy Market in Poland
Energies, 2021 It is because of competencies that there is a possibility of ensuring the strategic safety of each country when it comes to energy security. With the vast development of IT and teamwork, there are various competencies needed in the whole energy sector ...
Robert Szydło +5 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Training Policies for Vulnerable Groups in Central and Eastern European Countries [PDF]
, 2003 [From Preface] Since 1989, the countries of Central and Eastern Europe have faced both challenges and opportunities in the field of human resource development.
International Labour Office
core +1 more source
, 2022 AbstractThis chapter will focus on labour migration, that is the movement of persons with the aim of employment or income-bringing activities (e.g., entrepreneurship), developing the topic which was also touched upon in Chap. 3 on conceptual understanding of migration drivers. Research on labour migration has developed across various disciplines (e.g.,
Oso, Laura +2 more
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Global Employment Trends for Youth [PDF]
, 2006 [Excerpt] Young women and men are among the world’s greatest assets. They bring energy, talent and creativity to economies and create the foundations for future development.
International Labour Office
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source