Results 71 to 80 of about 1,980,146 (314)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

C111 Discrimination (Employment and Occupation) Convention, 1958 [PDF]

open access: yes, 1958
The General Conference of the International Labour Organisation, having been convened at Geneva by the Governing Body of the International Labour Office, and having met in its Forty-second Session on 4 June 1958 ...
International Labour Office
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Assessment of Teachers' Exposure to Noise in Selected Primary Schools

open access: yesArchives of Acoustics, 2013
The assessment of teachers' exposure to noise in primary schools was carried out on the basis of: questionnaire studies (covering 187 teachers in 3 schools), noise measurements at the teachers' workplaces, measurements of the school rooms acoustic ...
Danuta AUGUSTYŃSKA   +3 more
doaj  

Global Employment Trends: Brief, January 2006 [PDF]

open access: yes, 2006
[Excerpt] Despite robust GDP growth in 2005, labour market performance worldwide was mixed, with more people in work than in 2004 but at the same time more unemployed people than the year before. Overall the global unemployment rate remained unchanged at
International Labour Office
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

R168 Vocational Rehabilitation and Employment (Disabled Persons) Recommendation, 1983 [PDF]

open access: yes, 1983
The General Conference of the International Labour Organisation, having been convened at Geneva by the Governing Body of the International Labour Office and having met in its Sixty-ninth Session on 1 June 1983 ...
International Labour Office
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Accelerating Action Against Child Labour [PDF]

open access: yes, 2010
[Excerpt] The focus of this third Global Report on child labour under the follow-up to the ILO Declaration on Fundamental Principles and Rights at Work is about honouring the commitments made in 2006 with the adoption of a Global Action Plan.
International Labour Office
core   +1 more source

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