Results 161 to 170 of about 137,050 (353)

Strain‐Sensitive Thermochromic Smart Electronic Skin for Joint and Spine Healthcare Applications

open access: yesAdvanced Science, EarlyView.
iStretch, a multifunctional e‐skin integrating durable strain sensing, adaptive heat therapy, and visual feedback, is presented for joint and spine rehabilitation. Featuring a bilayer graphene–liquid metal design, iStretch offers high sensitivity, real‐time responsiveness, and user interactivity, enabling personalized musculoskeletal care through ...
Shicheng Fan   +5 more
wiley   +1 more source

Vinyl Acetate‐Enhanced Polyvinyl Chloride Gel with High Electroadhesion and Self‐Heating‐Tunability for Soft Robots in Freezing Environments

open access: yesAdvanced Science, EarlyView.
This study presents a vinyl acetate‐enhanced electroactive polyvinyl chloride gel with low‐voltage deformation, strong electro‐adhesion, and controlled heating. Leveraging these synergistic properties, this work develops soft robots capable of fast locomotion, swarm reconfiguration, and low‐temperature operation (‐50°C).
Chang Wei   +11 more
wiley   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

open access: yesAdvanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao   +14 more
wiley   +1 more source

Theoretical approach to labyrinth seal forces - cross-coupled stiffness of a straight-through labyrinth seal [PDF]

open access: yes
Two kinds of three dimensional flows in a labyrinth seal, a jet flow and a core flow, are considered and theoretical equations are set up concerning the motion of each flow.
Abe, T., Fujikawa, T., Kameoka, T.
core   +1 more source

Allele‐Specific Regulation of PAXIP1‐AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice

open access: yesAdvanced Science, EarlyView.
This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni   +14 more
wiley   +1 more source

Estrogen Alleviates Sevoflurane‐Induced Neurotoxicity by Inhibiting ERα‐Tau Binding

open access: yesAdvanced Science, EarlyView.
Sevoflurane‐induced neurotoxicity exhibits sex differences, and estrogen can mitigate these effects; however, its protective action appears to be time‐window dependent, which may be related to the competitive binding of estrogen and Tau to ERα. Abstract Sevoflurane‐induced neurotoxicity is age‐dependent, but the role of sex differences is unclear ...
Feixiang Li   +8 more
wiley   +1 more source

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