TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia
CNS Neuroscience &Therapeutics, EarlyView., 2023 Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi +19 more
wiley +1 more source
ChemMedChem, EarlyView.The synthesis of a new series of 4,5‐dihydrothiazol‐2‐ylphenylpiperazine derivatives as serotoninergic ligands is described and tested for their affinity toward 5‐HT1A, 5‐HT2A,and 5‐HT2C and selected for further in vivo assays to determine their functional activity. The pharmacological studies highlight that among the developed derivatives, FG‐7 and FG‐
Giorgia Andreozzi +18 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2016 BACKGROUND AND OBJECTIVE: Cyclophosphamide is a drug widely used to treat cancer, skin diseases and immune system disorders. Since cyclophosphamide passes placenta during pregnancy and causes disorders in fetus, this study was conducted to assess the ...
Z Rezaei +3 more
doaj
Potencial evocado miogênico vestibular ocular e cervical simultâneo em indivíduos normais
CoDASRESUMO Objetivo: Caracterizar o registro e analisar os resultados do potencial evocado miogênico vestibular cervical e ocular combinado em indivíduos sem queixas auditivas e vestibulares.
Tatiana Rocha Silva +2 more
doaj +1 more source
A head start: The relationship of placental factors to craniofacial and brain development
Developmental Dynamics, EarlyView.Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver +2 more
wiley +1 more source
Myocardial Infarction with Non-Obstructive Coronary Artery Disease: The Labyrinth of Investigations. Case Report and Review of the Literature [PDF]
, 2021 Paul Simion +5 more
openalex +1 more source
Maze‐Out: A Serious Game to Enhance Treatment for Eating Disorders. A Randomized Controlled Trial
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective This study evaluated the effectiveness of Maze Out, a serious game (SG) codesigned by patients with eating disorders (ED) and clinicians as an adjunct to treatment as usual (TAU) for improving self‐efficacy, self‐image, and engagement in individuals with ED.
Maria Mercedes Guala +7 more
wiley +1 more source
Acute respiratory failure as presentation of late-onset Pompe disease complicating the diagnostic process as a labyrinth: a case report [PDF]
, 2018 Francesco Menzella +5 more
openalex +3 more sources
The Labyrinth of Animals . (Including mammals, birds, reptiles and amphibians.) By Albert A. Gray, M.D., F.R.S.E., Surgeon for Diseases of the Ear to the Victoria Infirmary, Glasgow. London, J. & A. Churchill. 1907. Vol. I. Pp. 197; 31 stereoscopic photographs. [PDF]
, 1907 C. R. Bardeen
openalex +1 more source
ESC Heart Failure, EarlyView.Abstract Aims Atrial functional tricuspid regurgitation (AFTR) is increasingly recognized as a distinct cause of tricuspid regurgitation, yet data on outcomes and their determinants are limited. This study examines the prognostic role of right atrial (RA) remodelling in patients with severe AFTR.
Soongu Kwak +8 more
wiley +1 more source