Results 171 to 180 of about 9,217,738 (367)

Microglial Feimin Alleviates Cognitive Impairment in High‐Fat Diet‐Fed Mice

open access: yesAdvanced Science, EarlyView.
Microglial feimin deletion exacerbates lipotoxicity‐induced neuroinflammation and cognitive decline. In both in vitro and in vivo models, loss of feimin aggravated lipid droplet accumulation, IL‐1β/IL‐6 release, and neuronal injury through the PI3K–AKT–mTOR pathway, ultimately leading to severe neuronal apoptosis and cognitive impairment under high‐fat
Ran Gao   +12 more
wiley   +1 more source

Carbon Monoxide Nanomodulator Reverses Ischemia‐Reperfusion Injury in Stroke: A Novel Dual‐Channel Therapy Mode of Co‐driving Neuroprotection and Neurogenesis

open access: yesAdvanced Science, EarlyView.
This work develops a biomimetic and reactive oxygen species‐activated carbon monoxide (CO) nanogenerator to penetrate blood‐brain barrier, arrive in stroke‐affected regions, and release CO in a controlled manner for an innovative dual‐channel therapy strategy via co‐driving neuroprotection and neurogenesis.
Xuegang Niu   +17 more
wiley   +1 more source

Flight from the Fight? Civil War and its Effects on Refugees

open access: yes, 2015
Civil war dominates conflict in the modern era. An effect of this is a large number of refugees, who flee from war-torn countries in favor of lands where they can live in safety.
Lowry, Paul D.
core  

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

open access: yesAdvanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li   +10 more
wiley   +1 more source

Vestibular rehabilitation's effect over the quality of life of geriatric patients with labyrinth disease

open access: gold, 2008
Érika Barioni Mantello   +3 more
openalex   +1 more source

Potential welfare issues of the Siamese fighting fish (Betta splendens) at the retailer and in the hobbyist aquarium [PDF]

open access: yes, 2017
Betta splendens is an extremely popular ornamental fish among hobby aquarists. It has an interesting behavioral repertoire, particularly where male aggression and territoriality are concerned.
Moons, Christel, Pleeging, CCF
core   +1 more source

A Metalloporphyrin Nanosystem Enables Non‐Invasive Visualization and Specific Treatment for Thrombosis and Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
Thrombotic ischemic stroke is a severe neurological disease of the brain that presents major challenges for effective diagnosis and treatment. Precisely engineered Ir and Mn cores within a single porphyrin framework of 4IrMn nanoparticles enable endogenous ONOO−‐ or laser‐activated switching among NIR‐CL imaging, photothermal / photodynamic therapy ...
Ziwei Wang   +10 more
wiley   +1 more source

Influence of vestibular rehabilitation on the quality of life of individuals with labyrinth disease

open access: gold, 2022
Shirley Nogueira Soares   +4 more
openalex   +2 more sources

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