Results 81 to 90 of about 19,094 (297)

Can a regulatory instrument promote research and development into neglected diseases? A Policy Delphi Survey

open access: yes, 2012
Fehr A. Can a regulatory instrument promote research and development into neglected diseases? A Policy Delphi Survey. Bielefeld: University of Bielefeld; 2012.Background Rare diseases and neglected diseases are characterized by deficits in drug research ...
Fehr, Angela
core  

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

open access: yesAdvanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu   +4 more
wiley   +1 more source

The Axis of Progression of Disease

open access: yesCancer Informatics, 2014
Starting with genetic or environmental perturbations, disease progression can involve a linear sequence of changes within individual cells. More often, however, a labyrinth of branching consequences emanates from the initial events. How can one repair an
Alan M. Tartakoff, Di Wu
doaj   +1 more source

ΣΥΜΒΟΛΗ ΕΙΣ ΤΗΝ ΧΕΙΡΟΥΡΓΙΚΗΝ ΘΕΡΑΠΕΙΑΝ ΤΗΣ ΛΑΝΘΑΝΟΥΣΗΣ ΛΑΒΥΡΙΝΘΙΤΙΔΟΣ

open access: yes, 1973
THIS PAPER IS DEALING WITH THE INFLAMMATORY TYMPANOGENIC DISEASES OF THE LABYRINTH AND PARTICULARLY WITH THE LATENT LABYRINTHITIS.IT IS BASED ON ELEVEN CASES OF LATENT LABYRINTHITIS OF THE EAR, NOSE AND THROAT DEPARTMENT OF ATHENS UNIVERSITY, WHICH ...
Παπαβασιλείου, Αντώνιος
core   +1 more source

Dual Physiological Barriers Bypassed by a Silk‐Based Supramolecular Protein Delivery Platform for Neuroinflammation Mitigation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu   +5 more
wiley   +1 more source

STUDY OF POSITIONAL PAROXYSMAL NYSTAGMUS IN PATIENTS WITH DIZZINESS

open access: yes, 2023
<p>Of 548 patients with complaints of vertigo due to ENT pathology, diseases of the cardiovascular and nervous systems, 101 (18,5±1,6%) had positional paroxysmal nystagmus (PPN).
Normirova Nargiza Nazarovna   +3 more
core   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

Deficiency of antisense lncRNA Gm48853 resulted in embryonic lethality and impaired placental development in mice

open access: yesReproductive and Developmental Medicine, 2019
Objective: Long noncoding RNAs (lncRNAs) play important roles in embryonic development and in various diseases. Gm48853 is a predicted natural antisense lncRNA gene of unknown function.
Qi-Yun Qin   +4 more
doaj   +1 more source

Labyrinth diseases

open access: yes, 1989
ESCOLA PAULISTA MED SCH,DISC OTONEUROL,CJ 81,RUA DR ALCEAU DE CAMPOS RODRIGUES 309,CEP,BR-04544 SAO PAULO,SP,BRAZILESCOLA PAULISTA MED SCH,DISC OTONEUROL,CJ 81,RUA DR ALCEAU DE CAMPOS RODRIGUES 309,CEP,BR-04544 SAO PAULO,SP,BRAZILWeb of ...
Ganança, Mauricio Malavasi [UNIFESP]   +1 more
core  

Inner ear symptoms: can we use them to approach cardiovascular diseases?

open access: yes, 2014
Sensory organs are programmed to detect external stimuli, and inform about possible threats. In general, they are characterized by a complex architecture, a highly energy-requiring function, a peripheral location and a vascular supply depending on a ...
CICERO, ARRIGO FRANCESCO GIUSEPPE   +3 more
core   +1 more source

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