Results 111 to 120 of about 3,440 (255)

Utility of MRI quantitative analysis in assessment of audio-vestibular impairment. [PDF]

open access: yesActa Otorhinolaryngol Ital
Calandrelli R   +9 more
europepmc   +1 more source

Mesna in Otologic Surgery: Efficacy and Safety—A Scoping Review

open access: yesThe Laryngoscope, EarlyView.
PRISMA flow diagram indicating the process of systematic inclusion and exclusion of articles. ABSTRACT Objective Mesna (Sodium 2‐mercaptoethanesulfonate) is widely used as a mucolytic agent and uroprotective agent. Recently, its disulfide bond‐breaking property has been applied in otologic surgery to facilitate safer dissection of cholesteatoma and ...
Kevork H. Atamian   +4 more
wiley   +1 more source

Perampanel Blocks Transsynaptic α‐Synuclein Propagation and Neurodegeneration in a Mouse Model of Lewy Body Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Transsynaptic α‐synuclein propagation plays a crucial role in the progression of Lewy body disease. We previously demonstrated that an α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor antagonist, perampanel, blocks neuronal uptake of α‐synuclein preformed fibrils (PFFs) in an activity‐dependent manner.
Jun Ueda   +9 more
wiley   +1 more source

Timing Is Everything: How Subtle Timing Changes in MRI Echo Planar Imaging Can Significantly Alter Mechanical Vibrations and Sound Level

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Echo‐Planar Imaging (EPI) is central to fMRI, diffusion MRI, and many dynamic clinical applications, yet rapid gradient switching induces strong mechanical vibrations, generates acoustic noise, and contributes to ghosting artifacts—effects that intensify at ultra‐high fields.
Amir Seginer   +6 more
wiley   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear   +7 more
wiley   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

Sickle Cell Crisis-Induced Painless Bilateral Orbital Bone Infarction: A Case Report. [PDF]

open access: yesCase Rep Ophthalmol
Farson L   +6 more
europepmc   +1 more source

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