Results 51 to 60 of about 93,344 (216)
Sciences, Eaux & TerritoiresLe concept de « frontière lacustre » pose de nombreuses questions quand il s'agit de prendre en compte la diversité des enjeux aquatiques face aux problématiques environnementales et politiques contemporaines. D'une logique de séparation, il faut penser
Julien GAUTIER +2 more
doaj +1 more source
Australian Journal of Social Issues, EarlyView.ABSTRACT In Australia, governments fund Community Legal Centres (CLCs) as part of the legal assistance sector (LAS) to meet the ‘legal needs’ of people experiencing disadvantage who cannot afford private legal services. Persistent unmet demand for CLCs is well‐documented. As artificial intelligence (AI) is increasingly used in private legal practice to
Catherine Hastings +2 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Spinal muscular atrophy (SMA) is caused by deletions or mutations in the survival motor neuron 1 (SMN1) gene and subsequent reduction in the expression of survival motor neuron (SMN) protein. The disease is characterized by degeneration of α motor neurons and subsequent muscle atrophy.
Emma R. Sutton +4 more
wiley +1 more source
Blood SOD1 Activity in ALS Patients Receiving Tofersen Treatment
Annals of Neurology, EarlyView.Objective The antisense oligonucleotide tofersen is the first disease‐modifying drug for SOD1‐related amyotrophic lateral sclerosis (ALS) and was approved because of its ability to reduce SOD1 protein and neurofilament levels. The effect of tofersen on SOD1 activity is unclear but of clinical relevance because homozygous SOD1 mutations, linked to ...
Katharina Goehring +18 more
wiley +1 more source
Les espèces exotiques dans les lacs français métropolitains
Sciences, Eaux & TerritoiresLes invasions biologiques sont à la fois une cause et une conséquence des changements écologiques visibles au sein des lacs français. Après avoir clarifié les subtilités sémantiques liées à la définition des espèces exotiques et les mécanismes ...
Victor FROSSARD +12 more
doaj +1 more source
Angewandte Chemie, EarlyView.Die schnelle Parawasserstoff‐Hyperpolarisation in Kombination mit einfacher Verdünnung ermöglicht die Zufuhr von hyperpolarisiertem, biokompatiblen Pyruvats zu immobilisierten lebenden Zellen innerhalb von ≈1 min. Wiederholte Substratinjektionen offenbaren frequenzabhängige metabolische Dynamiken und eröffnen damit eine neue zeitliche Dimension für ...
Philipp R. Groß +17 more
wiley +1 more source
Sciences, Eaux & TerritoiresDans un contexte de tension croissante sur la ressource en eau, le développement de nouveaux outils de surveillance constitue un levier déterminant pour la mise en œuvre de politiques publiques efficaces.
Thierry TORMOS +8 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.Rapid parahydrogen hyperpolarization combined with simple dilution enables biocompatible delivery of hyperpolarized pyruvate to immobilized living cells within ≈1 min. Repeated substrate injections reveal frequency‐dependent metabolic dynamics, introducing a new temporal dimension for hyperpolarized NMR studies of cellular metabolism and enabling rapid
Philipp R. Groß +17 more
wiley +1 more source
Indian Journal of DermatologyBackground: India is a country with diverse religious and cultural practices instigating skin diseases which may be missed due to lack of awareness. Contact dermatitis (CD) to lac is not uncommon yet an underreported entity. Objectives: To study clinical
Neha Sharma +5 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract Fishes of the genus Enchodus were abundant and cosmopolitan in the Late Cretaceous, but are primarily known from isolated remains in Canada. Four well‐preserved fish skulls were recovered in recent years from ammolite mines sampling the Bearpaw Formation of Southern Alberta, and are here referred to Enchodus petrosus Cope, 1874.
Luke E. Nelson +2 more
wiley +1 more source