Results 91 to 100 of about 113,489 (230)

RNA polymerase structure and function at lac operon

Comptes Rendus. Biologies, 2005
Transcription of E. coli lac operon by RNA polymerase (RNAP) is a classic example of how the basic functions of this enzyme, specifically the ability to recognize/bind promoters, melt the DNA and initiate RNA synthesis, is positively regulated by transcription activators, such as cyclic AMP-receptor protein, CRP, and negatively regulated by lac ...
Sergei Borukhov, Jookyung Lee
openaire   +3 more sources

Citrate Supplementation Modulates Medium Viscosity and Poly‐γ‐Glutamic Acid Synthesis by Engineered B. subtilis 168

Engineering in Life Sciences, Volume 25, Issue 3, March 2025.
ABSTRACT The industrially attractive biopolymer poly‐γ‐glutamic acid (γ‐PGA) is commonly produced by species of the genus Bacillus by co‐feeding different carbon‐ and nitrogen‐sources. Recent studies have highlighted the pivotal role of co‐metabolization of a rapidly degradable carbon source such as glycerol together with citrate for γ‐PGA production ...
Frederik Völker, Kyra Hoffmann, Birthe Halmschlag, Sandra Maaß, Jochen Büchs, Lars M. Blank   +5 more
wiley   +1 more source

Metabolic insights of lactic acid bacteria in reducing off‐flavors and antinutrients in plant‐based fermented dairy alternatives

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 2, March 2025.
Abstract Multiple sensorial, technological, and nutritional challenges must be overcome when developing plant‐based fermented dairy alternatives (PBFDA) to mimic their dairy counterparts. The elimination of plant‐derived off‐flavors (green, earthy, bitter, astringent) and the degradation of antinutrients are crucial quality factors highlighted by the ...
Guillermo Eduardo Sedó Molina, Geoffrey Ras, Denise Felix da Silva, Lene Duedahl‐Olesen, Egon Bech Hansen, Claus Heiner Bang‐Berthelsen   +5 more
wiley   +1 more source

Identification, characterization and classification of prokaryotic nucleoid‐associated proteins

Molecular Microbiology, Volume 123, Issue 3, Page 206-217, March 2025.
Nucleoid‐associated proteins (NAPs) structure DNA by either bending, wrapping, bridging, or forming protein filaments on the DNA. We review newly identified NAPs and provide a list of simple biochemical assays to study the DNA‐structuring properties of novel NAPs. Abstract Common throughout life is the need to compact and organize the genome.
Samuel Schwab, Remus T. Dame
wiley   +1 more source

Pre‐dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch

Molecular Systems Biology, 2010
The lactose operon regulation in Escherichia coli is a primary model of phenotypic switching, reminiscent of cell fate determination in higher organisms.
Lydia Robert, Gregory Paul, Yong Chen, François Taddei, Damien Baigl, Ariel B Lindner   +5 more
doaj   +1 more source

Subpopulations of sensorless bacteria drive fitness in fluctuating environments.

PLoS Biology, 2020
Populations of bacteria often undergo a lag in growth when switching conditions. Because growth lags can be large compared to typical doubling times, variations in growth lag are an important but often overlooked component of bacterial fitness in ...
Thomas Julou, Ludovit Zweifel, Diana Blank, Athos Fiori, Erik van Nimwegen   +4 more
doaj   +1 more source

The lac operon in the wild

, 2017
The lac operon is a classic model system for bacterial gene regulation, and has been studied extensively in E. coli, a classic model organism. However, not much is known about E. coli’s ecology and life outside the laboratory, in particular in soil and water environments.
openaire   +2 more sources

Regulation of nucleus‐encoded trans‐acting factors allows orthogonal fine‐tuning of multiple transgenes in the chloroplast of Chlamydomonas reinhardtii

Plant Biotechnology Journal, Volume 23, Issue 3, Page 1005-1018, March 2025.
A strain of Chlamydomonas has been generated that allows independent regulation of two genes in the chloroplast by addition of vitamins B12 and thiamine to the culture medium. Summary The green microalga Chlamydomonas reinhardtii is a promising host organism for the production of valuable compounds.
Pawel Mateusz Mordaka, Kitty Clouston, Aleix Gorchs‐Rovira, Catherine Sutherland, Daniel Qingyang Zhang, Katrin Geisler, Payam Mehrshahi, Alison Gail Smith   +7 more
wiley   +1 more source

Identification of an intestine-specific promoter and inducible expression of bacterial α-galactosidase in mammalian cells by a lac operon system

Journal of Animal Science and Biotechnology, 2012
Background α-galactosidase has been widely used in animal husbandry to reduce anti-nutritional factors (such as α-galactoside) in feed. Intestine-specific and substrate inducible expression of α-galactosidase would be highly beneficial for transgenic ...
Ya-Feng Zhai, Gang Shu, Xiao-Tong Zhu, Zhi-Qi Zhang, Xia-Jing Lin, Song-Bo Wang, Li-Na Wang, Yong-Liang Zhang, Qing-Yan Jiang   +8 more
doaj   +1 more source

Synchrony in a Boolean network model of the L-arabinose operon in Escherichia coli [PDF]

arXiv, 2016
The lactose operon in Escherichia coli was the first known gene regulatory network, and it is frequently used as a prototype for new modeling paradigms. Historically, many of these modeling frameworks use differential equations. More recently, Stigler and Veliz-Cuba proposed a Boolean network model that captures the bistability of the system and all of
arxiv