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1996
In 1961, Jacob and Monod proposed the operon model of gene expression and its negative control primarily from the experimental results obtained by these authors and their colleagues studying the induced synthesis of proteins involved in the utilization of sugar lactose and development of bacteriophage X from a prophage state in Escherichia coli.
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In 1961, Jacob and Monod proposed the operon model of gene expression and its negative control primarily from the experimental results obtained by these authors and their colleagues studying the induced synthesis of proteins involved in the utilization of sugar lactose and development of bacteriophage X from a prophage state in Escherichia coli.
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Characteristics of tight binding repressors of the lac operon
Journal of Molecular Biology, 1981Abstract A number of tight binding lac repressor mutants (Itb) have been analyzed. The mutant repressors could be shown to have altered DNA binding properties, which can include an increased affinity for operator DNA, an increased affinity for non-specific DNA, or a decreased affinity for non-specific DNA.
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Designing Biological Circuits: Synthetic Biology Within the Operon Model and Beyond
Annual Review of Biochemistry, 2021Max A English, James J Collins
exaly
Magnetic fields affect the lac operon system
Physics in Medicine & Biology, 1982E, Aarholt, E A, Flinn, C W, Smith
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The Mechanism of Activation of the Lac Operon
1972The lac operon consists of a cluster of genes found on the single chromosome of the bacterium Escherichia coli. Starting from one side the cluster contains a promoter, an operator, the structural genes for β-galactosidase, permease and thiogalactoside transacetylase.1 Such a grouping of regulating and structural genes is termed an operon. In 1961 Jacob
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Understanding the lac operon with GeneAct
International Journal of Computational Biology and Drug Design, 2015Xiaoli Yang +3 more
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Optogenetic control of the lac operon for bacterial chemical and protein production
Nature Chemical Biology, 2020Makoto A Lalwani +2 more
exaly