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Genetic and structural insights into the functional importance of the conserved gly-met-rich C-terminal tails in bacterial chaperonins. [PDF]
Commun BiolKumar CMS, Mai AM, Mande SC, Lund PA.
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Carbon upshift in <i>Lactococcus cremoris</i> elicits immediate initiation of proteome-wide adaptation, coinciding with growth acceleration and pyruvate dissipation switching. [PDF]
mBiovan Olst B +3 more
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Proteolytic stability and aggregation in a key metabolic enzyme of bacteria. [PDF]
Proc Natl Acad Sci U S APollack D, Nozoe T, Kussell E.
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Case Studies in Systems Biology, 2021
The lac operon regulatory mechanism allows bacteria to sense external nutrient conditions and, accordingly, regulate gene transcription that assists in the digestion of available nutrients. The lac system produces a switch-like dynamic behavior, where the switching between ‘on’ and ‘off’ states of lac gene transcription depends on the specific ...
P. Kraikivski
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The lac operon regulatory mechanism allows bacteria to sense external nutrient conditions and, accordingly, regulate gene transcription that assists in the digestion of available nutrients. The lac system produces a switch-like dynamic behavior, where the switching between ‘on’ and ‘off’ states of lac gene transcription depends on the specific ...
P. Kraikivski
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Journal of Molecular Biology, 2013
The ability to regulate gene expression is essential for controlling metabolic events in a cell. Proteins that function like molecular switches respond to fluctuations in the environment to maintain homeostasis. The operon model, proposed by Jacob and Monod, provides a cogent depiction for how gene expression is regulated. A molecular mechanism for the
M. Lewis
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The ability to regulate gene expression is essential for controlling metabolic events in a cell. Proteins that function like molecular switches respond to fluctuations in the environment to maintain homeostasis. The operon model, proposed by Jacob and Monod, provides a cogent depiction for how gene expression is regulated. A molecular mechanism for the
M. Lewis
openaire +4 more sources
Isolation of Pure lac Operon DNA*
Nature, 1969Two specialized transducing phages, which carry the lac operon of Escherichia coli inserted into their DNA in opposite orientations, are used as a source of complementary sequences from which to prepare pure lac operon duplex. The availability of a single pure promoter will facilitate many new experiments on genetic transcription.
Larry Eron +8 more
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ACS Synthetic Biology, 2022
Lac operon is the standard regulator used to control the orthogonality of T7RNA polymerase (T7RNAP) and T7 promoter inEscherichia coli BL21(DE3) strain for protein expression. However,E. coliNissle 1917 (EcN), the unique probiotic strain, has seldom been
S. S. W. Effendi, I. Ng
semanticscholar +1 more source
Lac operon is the standard regulator used to control the orthogonality of T7RNA polymerase (T7RNAP) and T7 promoter inEscherichia coli BL21(DE3) strain for protein expression. However,E. coliNissle 1917 (EcN), the unique probiotic strain, has seldom been
S. S. W. Effendi, I. Ng
semanticscholar +1 more source
Modeling Gene Expression: Lac operon
2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2021Gene regulation is an essential process for cell development, having a profound effect in dictating cell functions. Bacterial genes are often regulated through inducible systems like the Lac operon which plays an important role in cell metabolism. An accurate model of its regulation can reveal the dynamics of gene expression.
Sarai, Velazco +6 more
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Catabolite Sensitive Site of the lac Operon
Nature, 1969A partial deletion in the lac p region makes the lac operon insensitive to catabolite repression.
Allen E. Silverstone +4 more
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