Results 211 to 220 of about 128,431 (240)
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Hopf Bifurcation and Delay-Induced Turing Instability in a Diffusive lac Operon Model
International Journal of Bifurcation and Chaos in Applied Sciences and Engineering, 2016In this paper, we investigate the dynamics of a lac operon model with delayed feedback and diffusion effect. If the system is without delay or the delay is small, the positive equilibrium is stable so that there are no spatial patterns formed; while the ...
Xin Cao, Yongli Song, Tonghua Zhang
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Biotechnology and Bioengineering, 2022
2'‐Fucosyllactose (2'‐FL) is the most abundant oligosaccharide in human milk and one of the most actively studied human milk oligosaccharides (HMOs). When 2'‐FL is produced through biological production using a microorganism, like Escherichia coli, d ...
B. S. Park +7 more
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2'‐Fucosyllactose (2'‐FL) is the most abundant oligosaccharide in human milk and one of the most actively studied human milk oligosaccharides (HMOs). When 2'‐FL is produced through biological production using a microorganism, like Escherichia coli, d ...
B. S. Park +7 more
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Understanding the lac operon with GeneAct
Int. J. Comput. Biol. Drug Des., 2015GeneAct is a new framework developed to accelerate the coding of interactive programs for learning genetics. In this paper, the framework is used to create an interactive program for understanding the lac operon.
Xiaoli Yang +3 more
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ACS Synthetic Biology, 2013
The basic methodology for designing, altering, and constructing biological systems is increasingly relying on well-established engineering principles to move forward from trial and error approaches to reliably predicting the system behavior from the ...
J. Vilar, L. Saiz
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The basic methodology for designing, altering, and constructing biological systems is increasingly relying on well-established engineering principles to move forward from trial and error approaches to reliably predicting the system behavior from the ...
J. Vilar, L. Saiz
semanticscholar +1 more source
Studies on the in vitro transcription and translation of the lac operon
Archives of Biochemistry and Biophysics, 1974With the use of rifampicin to stop the initiation of RNA synthesis, the in vitro synthesis of β -galactosidase has been carried out in two separate stages, transcription and translation. In this system it has been possible to examine whether substances, which affect the synthesis of the enzyme, function at the transcription or translation level of ...
Hsiang-Fu Kung +4 more
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Genetic mapping of a new promoter for the lac operon
Journal of Molecular Biology, 1975Abstract A mutation (or group of mutations) necessary for the synthesis of increased quantities of lac mRNA has been localized within the structural gene for the lac repressor ( lacI ). This mutation is probably a new cyclic AMP-binding protein-dependent promoter within the I gene.
Paula De Lucia-Curtin, Jeremy Bruenn
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The Mechanism of Activation of the Lac Operon
1972The lac operon consists of a cluster of genes found on the single chromosome of the bacterium Escherichia coli. Starting from one side the cluster contains a promoter, an operator, the structural genes for β-galactosidase, permease and thiogalactoside transacetylase.1 Such a grouping of regulating and structural genes is termed an operon. In 1961 Jacob
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Dynamics and bistability in a reduced model of the lac operon
Chaos: An Interdisciplinary Journal of Nonlinear Science, 2004It is known that the lac operon regulatory pathway is capable of showing bistable behavior. This is an important complex feature, arising from the nonlinearity of the involved mechanisms, which is essential to understand the dynamic behavior of this molecular regulatory system.
Daisuke Horike +3 more
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Characteristics of tight binding repressors of the lac operon
Journal of Molecular Biology, 1981Abstract A number of tight binding lac repressor mutants (Itb) have been analyzed. The mutant repressors could be shown to have altered DNA binding properties, which can include an increased affinity for operator DNA, an increased affinity for non-specific DNA, or a decreased affinity for non-specific DNA.
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1996
In 1961, Jacob and Monod proposed the operon model of gene expression and its negative control primarily from the experimental results obtained by these authors and their colleagues studying the induced synthesis of proteins involved in the utilization of sugar lactose and development of bacteriophage X from a prophage state in Escherichia coli.
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In 1961, Jacob and Monod proposed the operon model of gene expression and its negative control primarily from the experimental results obtained by these authors and their colleagues studying the induced synthesis of proteins involved in the utilization of sugar lactose and development of bacteriophage X from a prophage state in Escherichia coli.
openaire +2 more sources