Results 111 to 120 of about 43,463 (274)

Immunological and Clinical Effect of Diet Modulation of the Gut Microbiome in Multiple Sclerosis Patients: A Pilot Study

Frontiers in Immunology, 2017
Pathogenesis of autoimmune disorders, including multiple sclerosis (MS), has been linked to an alteration of the resident microbial commensal community and of the interplay between the microbiota and the immune system.
Marina Saresella, Laura Mendozzi, Valentina Rossi, Franca Mazzali, Federica Piancone, Francesca LaRosa, Ivana Marventano, Domenico Caputo, Giovanna E. Felis, Mario Clerici, Mario Clerici   +10 more
doaj   +1 more source

Nanoformulated Diacerein Alleviates Hyperlipidemia via Gut Microbiota Modulation In Vivo

Nano Select, EarlyView.
A nanoformulation of diacerein (Nano‐DIA) was fabricated with carboxymethyl cellulose, achieving enhanced solubility and rapid dissolution for alternative anti‐hyperlipidemia therapeutics. Mechanistic studies revealed its in vivo lipid‐lowering efficacy is through metabolite‐mediated and microbiota‐dependent manner, highlighting its dual action on host
Zheng Peng, Yi Yu, Mingyi Chen, Weibin Wu, Chunyan Zhu, Caisheng Wu, Weihua Li, Zehua Liu, Qiang Xie   +8 more
wiley   +1 more source

Prebiotic, Probiotic, and Synbiotic Supplementation in Chronic Kidney Disease: A Systematic Review and Meta-analysis [PDF]

, 2019
Gut dysbiosis has been implicated in the pathogenesis of chronic kidney disease (CKD). Restoring gut microbiota with prebiotic, probiotic, and synbiotic supplementation has emerged as a potential therapeutic intervention but has not been systematically ...
Campbell, Katrina L., Johnson, David W., McFarlane, Catherine, Ramos, Christiane I.   +3 more
core   +1 more source

Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease

eLife, 2019
The secretion of peptides and proteins is essential for survival and ecological adaptation of bacteria. Dual-functional ATP-binding cassette transporters export antimicrobial or quorum signaling peptides in Gram-positive bacteria.
Silvia C Bobeica, Shi-Hui Dong, Liujie Huo, Nuria Mazo, Martin I McLaughlin, Gonzalo Jiménez-Osés, Satish K Nair, Wilfred A van der Donk   +7 more
doaj   +1 more source

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

PM&R, EarlyView.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang, Qing Kuang, Cheng Chen, Binru Wang, Wei Xiang, Xinming Li, Jianjiao Mou   +6 more
wiley   +1 more source

Gut Microbiota’s role in lipoma development: evidence from mendelian randomization

Frontiers in Genetics
BackgroundLipoma, a benign tumor derived from mesenchymal tissue, significantly affects patients’ physical and psychological wellbeing. Increasing evidence points to a strong link between the gut microbiome (GM) and lipoma incidence.
Yuxin Li, Jiahao Chen, Hang Yao, Xiaogang Xu, Xianglong Zheng, Yu Wang, Wanchun Wang, Wanchun Wang   +7 more
doaj   +1 more source

Single and dual RPA‐CRISPR/Cas assays for point‐of‐need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus

Pest Management Science, Volume 81, Issue 4, Page 1988-1999, April 2025.
Schematic diagram of the single and dual RPA‐CRISPR/Cas12a/13a diagnostic assays for the detection of Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus. The validated assays provide a useful and sensitive molecular tool for detecting two quarantine pathogens of maize within a minimal resource framework suitable for fast‐tracking the ...
Qian Tian, Hua Zhou, Zhenxing Zhao, Yongjiang Zhang, Wenjun Zhao, Lulu Cai, Tao Guo   +6 more
wiley   +1 more source

Small amounts of misassembly can have disproportionate effects on pangenome-based metagenomic analyses

mSphere
Individual genes from microbiomes can drive host-level phenotypes. To help identify such candidate genes, several recent tools estimate microbial gene copy numbers directly from metagenomes.
Stephanie N. Majernik, Larry Beaver, Patrick H. Bradley   +2 more
doaj   +1 more source

Butyribacter intestini gen. nov., sp. nov., a butyric acid-producing bacterium of the family Lachnospiraceae isolated from the human faeces, and reclassification of Acetivibrio ethanolgignens as Acetanaerobacter ethanolgignens gen. nov., comb. nov [PDF]

, 2020
Wenbin Xue, Xiaoqian Lin, Mei Lv, Guangwen Luo, Ying Dai, Haipeng Sun, Liang Xiao, Yuanqiang Zou   +7 more
openalex   +1 more source

Sewage reflects the microbiomes of human populations [PDF]

, 2015
© The Author(s), 2015. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in mBio 6 (2015): e02574-14, doi:10.1128/mBio.02574-14.Molecular characterizations of the gut microbiome ...
Dila, Deborah K., Eren, A. Murat, McLellan, Sandra L., Morrison, Hilary G., Newton, Ryan J., Sogin, Mitchell L., Vineis, Joseph H.   +6 more
core   +2 more sources