Results 141 to 150 of about 43,463 (274)
Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications
MedComm, Volume 7, Issue 2, February 2026.The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin +12 more
wiley +1 more source
Prolonged Antibiotic Use in a Preclinical Model of Gulf War Chronic Multisymptom-Illness Causes Renal Fibrosis-like Pathology via Increased micro-RNA 21-Induced PTEN Inhibition That Is Correlated with Low Host Lachnospiraceae Abundance [PDF]
, 2023 Ayushi Trivedi +7 more
openalex +1 more source
The Gut Microbiota as a Mediator in the Relationship Between Dietary Patterns and Depression
MedComm, Volume 7, Issue 2, February 2026.Healthy dietary patterns are associated with gut microbial genera linked to lower depressive symptoms. In 644 older adults from the PREDIMED‐Plus cohort, 16S rRNA sequencing and dietary scoring revealed that taxa associated with a better diet quality were also more abundant in individuals with fewer depressive symptoms.
Adrián Hernández‐Cacho +16 more
wiley +1 more source
Microbes and environments, 2014 The aim of the present study was to identify bacteria that may contribute to the onset of metabolic dysfunctions. We isolated and identified a candidate bacterium belonging to Lachnospiraceae (strain AJ110941) in the feces of hyperglycemic obese mice.
Kameyama, Keishi, Itoh, Kikuji
openaire +2 more sources
Role of Acid‐Sensing Ion Channels 1a in the Regulation of Obesity and the Gut Microbiota
Obesity, Volume 34, Issue 2, Page 372-381, February 2026.ABSTRACT Objective Acid‐sensing ion channels are proton‐activated ion channels predominantly found in the nervous system. They are well known to affect metabolic and neurological health, yet their role in obesity and gut physiology remains unclear. This study investigates how systemic deletion of Asic1a influences obesity, metabolic, and gut‐based ...
Jane Shearer +7 more
wiley +1 more source
Aging Cell, Volume 25, Issue 2, February 2026.This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá +5 more
wiley +1 more source
Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions
Aging Cell, Volume 25, Issue 2, February 2026.Hematopoietic aging arises from intrinsic stem‐cell decline and bone‐marrow niche dysfunction, leading to myeloid skewing, immunosenescence, and clonal hematopoiesis. These changes drive systemic inflammation and multi‐organ disease, which in turn further disrupt the bone‐marrow niche and hematopoietic stem cell (HSC) function, creating a vicious cycle
Masashi Miyawaki +3 more
wiley +1 more source
Gut microbiome diversity within Clostridia is negatively associated with human obesity
mSystemsClostridia are abundant in the human gut and comprise families associated with host health such as Oscillospiraceae, which has been correlated with leanness.
Laura Salazar-Jaramillo +6 more
doaj +1 more source