Results 151 to 160 of about 43,463 (274)

Integrating Transcriptomics and Gut Microbiota Analysis Reveals the Anti‐Osteoporotic Mechanisms of Wine and Oil Co‐Processed Epimedium

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Firstly, we determined the content of the components in the co‐products of Epimedium wine and oil. Secondly, the clinical indications of the co‐products of Epimedium wine and oil were determined by in vitro cell experiments. Finally, the in vivo animal model was used for experimental verification.
Jinling Liang, Shichang Li, Yulin Dai, Zifeng Pi, Jia Liu, Pan Li, Weixia Sun, Tao Jiang, Tianyang Xu, Peng Yu   +9 more
wiley   +1 more source

P069 Elevated adaptive immune responses to multiple Lachnospiraceae bacterial flagellins in therapy-naïve pediatric CD patients are associated with distinct immune pathology. [PDF]

, 2023
D Barendregt, Maria E. Joosse, Katie L. Alexander, L M M Costes, Irma Tindemans, Y. Simons‐Oosterhuis, M Aardoom, R Klomberg, M Heredia, D H Hulleman- van Haaften, Bastiaan Tuk, Sandrine Nugteren, Michail Doukas, J.C. Escher, Lissy de Ridder, Charles O. Elson, J N Samsom   +16 more
openalex   +1 more source

Faecalibaculum rodentium Alleviates Ionizing Radiation‐Induced Damage in Mice by Improving Intestinal Integrity and Hematopoiesis via Its Metabolite Butyrate

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The model shows the probiotics screening and underlying mechanisms of F. rodentiumn in alleviating IR‐induced tissue injury. Stress‐induced STAT3 mitochondria localization decreases F. rodentium abundance and butyrate concentration. Supplementation of F.
Hanyong Zhu, Hui Guo, Na Sun, Rui Xiao, Binbin Ji, Ruihan Jiang, Fuxing Dong, Chen Yao, Xuerong Wang, Rongqing Li, Jie Zhao, Xueqin Li, Shengzhe Gong, Yongqin Qin, Xin Chen, Yuchen Pan, Takayuki Ikezoe, Jing Yang   +17 more
wiley   +1 more source

Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park, Min‐Ji Kim, Jae‐Ho Shin, Eunsoo Kim, Myeongjoo Son, Seungjun Lee   +5 more
wiley   +1 more source

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source

Gut proteome and microbiome alterations: Analysis of transverse colon samples from pathologically confirmed Alzheimer's disease patients

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) has been regarded as a brain‐first disorder. Emerging evidence suggests that the gut may influence central nervous system pathology, but the mechanisms remain unclear. METHODS We conducted a proteomic and microbial analysis of transverse colon samples from clinically and pathologically confirmed AD and ...
Qiwen Cheng, Jennifer Nolz, Timothy Karr, Nicole Dorn, Benjamin Readhead, Rosa Krajmalnik‐Brown, Diego Mastroeni   +6 more
wiley   +1 more source

The microbiota–gut–brain axis in mild cognitive impairment and Alzheimer's disease: a scoping review of human studies

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract Alzheimer's disease (AD) is projected to become the highest‐burden neurological disorder globally. Mounting evidence implicates the gut microbiome in AD pathogenesis. This scoping review of gut microbiomes in mild cognitive impairment (MCI) and AD included dietary and probiotic interventions.
Alison Warren, Zan Wynia, Patrick G. Corr, Mershad Fahim Devin, Zeynep Celikkol, Lindsey Gordon, Mina Farah, Michaela Karam, Daniel Villarreal, Scott A. Jackson, Leigh A. Frame   +10 more
wiley   +1 more source

Causal relationship between gut microbiota and male erectile dysfunction: a Mendelian randomization analysis

Frontiers in Microbiology
BackgroundSeveral observational studies have reported an association between gut microbiota and male erectile dysfunction (ED). However, it remains unclear whether there is a causal relationship between gut microbiota and male ED.
Shuaiqi Chen, Shuaiqi Chen, Xiaolong Liu, Shangrong Wu, Guangyu Sun, Ranlu Liu   +5 more
doaj   +1 more source

HDL-C as a potential medium between depletion of Lachnospiraceae genera and hypertension under high-calorie diet [PDF]

, 2022
Yongmei Lan, Kang Ning, Yanqing Ma, Jin Zhao, Caihong Ci, Xiao Yang, Fulong An, Zilong Zhang, Yan An, Mingyue Cheng   +9 more
openalex   +1 more source

Identifying Immune Cells as Mediators in the Impact of Gut Microbiota on Congenital Malformations of the Nervous System

Brain and Behavior, Volume 16, Issue 1, January 2026.
This study reveals causal links between gut microbiota and congenital nervous system malformations, identifying nine immune cell types, such as CD20+ and CD25+ B cells, as mediators, highlighting gut–immune interactions as potential preventive or therapeutic targets.
Haokun Tian, Xiaolan Guo, Jialu Yu, Yuanfang Lu, Wensen Cao, Xiuwei Wang, Zhiqiang Zhu, Zhen Guan, Aiyun Yang, Shen Li, Xiaochun Xu, Caihua Wang, Jianhua Wang   +12 more
wiley   +1 more source