Results 161 to 170 of about 43,463 (274)

Lachnospiraceae-mediated bile acid metabolism promotes ileal epithelial regeneration following graft-versus-host disease damage [PDF]

Tomo Hayase, Achouak Achour, Rasoul Pourebrahim, Robert R. Jenq, Leo Luznik, Eiko Hayase   +5 more
openalex   +1 more source

Distinct Gut Microbiota Profiles Reflect Severity in Chronic Insomnia Disorder

Brain and Behavior, Volume 16, Issue 1, January 2026.
The authors used 16S rRNA sequencing and PICRUSt2 analysis to explore the link between sleep quality and gut microbiota in chronic insomnia disorder (CID) patients. Those with more severe sleep disturbances exhibited pronounced gut microbiota dysbiosis (structural/functional alterations).
Yaxi Liu, Yixian Cai, Xian Shi, Mei Fan, Xiaotao Zhang, Jingjing Lin, Xiaoxuan Fan, Bingdong Liu, Jiyang Pan   +8 more
wiley   +1 more source

Exploring the Fecal Microbiome Dysbiosis and Its Plasma Metabolome Determinants in Advanced Parkinson's Disease With Motor Complications

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Our multiomics analysis across three PD cohorts revealed distinct fecal microbiome and plasma metabolome alterations in patients with motor complications (PD‐MC). We identified specific microbial and metabolic biomarkers and uncovered significant correlations between them, providing new insights into PD‐MC pathophysiology. ABSTRACT Background Parkinson'
Shuangjie Qian, Jialong Hou, Xi Xiong, Qi Duan, Tao Jiang, Yi Zheng, Weiwei Quan, Jiaxue Xu, Keke Chen, Jingjing Qian, Hongchang Gao, Chenglong Xie   +11 more
wiley   +1 more source

Baseline multi‐omics signatures could predict therapeutic response to neoadjuvant anti‐PD‐1 immunochemotherapy in non‐small‐cell lung cancer

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Overview of study design. Metagenomic and plasma/fecal metabolomic studies were performed in 44 NSCLC patients who underwent neoadjuvant tislelizumab therapy plus platinum ‐ based doublet chemotherapy. Abstract Background Neoadjuvant anti‐programmed cell death 1 (PD‐1) immunochemotherapy has shown promising efficiency in the treatment of early‐stage ...
Ailing Cao, Yaobin Lin, Shaoxing Guan, Youhao Chen, Wenyu Zhai, Yuheng Zhou, Shoucheng Feng, Yanping Guan, Yiyu Zhang, Min Huang, Xueding Wang, Hao Long   +11 more
wiley   +1 more source

Inclusion of Tenebrio molitor larvae meal in the diet of barbary partridge (Alectoris barbara) improves caecal bacterial diversity and composition

Scientific Reports
In this study, we investigated the influence of the inclusion of Tenebrio molitor (TM) larvae meal in the diet on the diversity and structure of the bacterial community in the caecal content of Barbary partridges.
Tiziana Maria Mahayri, Elie Atallah, Kateřina Olša Fliegerová, Jakub Mrázek, Giovanni Piccolo, Fulvia Bovera, Giuseppe Moniello   +6 more
doaj   +1 more source

Bacteroidota and Lachnospiraceae Integration Into the Gut Microbiome at Key Time Points in Early Life are Critical for Neurodevelopment [PDF]

, 2021
Kaitlyn Oliphant, Mehneez Ali, Mark D’Souza, Patrick D. Hughes, Dinanath Sulakhe, Annie Z. Wang, Bingqing Xie, Rummanu Yeasin, Michael E. Msall, Bree Andrews, Erika C. Claud   +10 more
openalex   +1 more source

DSOK‐0011 Potentially Regulates Circadian Misalignment and Affects Gut Microbiota Composition in Activity‐Based Anorexia Model

International Journal of Eating Disorders, Volume 59, Issue 1, Page 54-69, January 2026.
ABSTRACT Objective Anorexia nervosa (AN) is a metabolic‐psychiatric disorder characterized by severe weight loss, hypercortisolemia, and hypothalamic–pituitary–adrenal (HPA) axis activation. In this study, we investigated the effect of inhibiting cortisol regeneration via the enzyme 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1) on the ...
Hiroki Kawai, Nanami Wada, Shinji Sakamoto, Kenji Miyazaki, Taro Kato, Yoshihiro Horiuchi, Hiroshi Kirii, Hoang Duy Nguyen, Kenji Hinotsu, Yoshio Ohya, Takahiro Asada, Akiyoshi Yokode, Yuko Okahisa, Haruko Miyazaki, Toshitaka Oohashi, Manabu Takaki   +15 more
wiley   +1 more source

Moxifloxacin Induced Liver Injury by Causing Lachnospiraceae Deficiency and Interfering with Butyric Acid Production through Gut–Liver Axis [PDF]

, 2022
Yuan Sun, Ling Cong, Yang Song, Rui Zhao, Zhuoling An, Lihong Liu   +5 more
openalex   +1 more source

New Insights Into Ginseng and Clove Supplementation: Alleviating Obesity by Reducing Leptin Resistance and Reshaping the Gut Microbiota

Food Frontiers, Volume 7, Issue 1, January 2026.
AEGC conferred substantial resistance to weight gain and reduced food intake. AEGC may alleviate LR by regulating the levels of LEP and ADP. AEGC elevated the diversity of gut microbiota and reconstructed the composition. Changes such as CAG‐873 in gut microbiota may be the reason why AEGC alleviates LR.
Weifeng Ni, Shen Yao, Shichao Li, Shichao Liu, Liwei Sun, Daqing Zhao, Zhengqi Dong, Siming Wang, Weinan Wang, Meichen Liu   +9 more
wiley   +1 more source

A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria

, 2013
Conor J. Meehan, Robert G. Beiko
openalex   +1 more source