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Human-Associated Lachnospiraceae Genetic Markers Improve Detection of Fecal Pollution Sources in Urban Waters [PDF]

Applied and Environmental Microbiology, 2018
Traditional fecal indicator bacteria do not distinguish animal from human fecal pollution, which is necessary to evaluate health risks and mitigate pollution sources. Assessing water in urban areas is challenging, since the water can be impacted by sewage, which has a high likelihood of carrying human pathogens, as well as pet and urban wildlife waste.
Sandra L Mclellan
exaly   +3 more sources

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Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance

Cell Host & Microbe, 2023
The intestinal microbiota plays an important role in colorectal cancer (CRC) progression. However, the effect of tissue-resident commensal bacteria on CRC immune surveillance remains poorly understood. Here, we analyzed the intratissue bacteria from CRC patient colon tissues. We found that the commensal bacteria belonging to the Lachnospiraceae family,
Xusheng Zhang, Dou Yu, Di Wu, Xintong Gao, Fei Shao, Min Zhao, Jiang Wang, Jiangwen Ma, Wenzhao Wang, Xiwen Qin, Yi Chen, Pengyan Xia, Shuo Wang   +12 more
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Oribacterium sinus gen. nov., sp. nov., within the family ‘Lachnospiraceae’ (phylum Firmicutes)

International Journal of Systematic and Evolutionary Microbiology, 2004
A hitherto unknown anaerobic bacillus isolated from sinus pus in a young child (strain AIP 354.02T) was characterized by using phenotypic and genotypic methods. 16S rRNA gene sequence analysis indicated that this strain was phylogenetically affiliated with several sequences of cloned 16S rRNA gene inserts previously deposited in the public databases ...
Jean-Philippe, Carlier, Guylène, K'ouas, Isabelle, Bonne, Alain, Lozniewski, Francine, Mory   +4 more
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Ginseng polysaccharides ameliorate colorectal tumorigenesis through Lachnospiraceae-mediated immune modulation

International Journal of Biological Macromolecules
Probiotics and their metabolites play a critical role in immunotherapy for colorectal cancer (CRC) and intestinal damage. Identifying specific probiotics from natural products and elucidating the underlying mechanisms represent promising strategies for CRC research.
Gangfan, Zong, Rui, Deng, Yehua, Pan, Mingyuan, Liu, Hongzheng, Zhu, Ruizhi, Tao, Yunlong, Shan, Zhonghong, Wei, Yin, Lu   +8 more
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‘ Candidatus Arthromitus’ revised: segmented filamentous bacteria in arthropod guts are members of Lachnospiraceae

Environmental Microbiology, 2012
Summary The name Arthromitus has been applied collectively to conspicuous filamentous bacteria found in the hindguts of termites and other arthropods. First observed by Joseph Leidy in 1849, the identity of these filaments has remained contentious.
Thompson, C., Vier, R., Mikaelyan, A., Wienemann, T., Brune, A.   +4 more
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Lachnospiraceae bacterium TF01-11 Genome sequencing

2015
Genome of a novel bacteria species isolated from Shenzhen China.
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Prematurely delivering mothers show reductions of Lachnospiraceae in their gut microbiomes

2022
This study analyzed the taxonomic composition and metabolic function in gut microbial communities between preterm mothers and term mothers, coupled with shotgun metagenomic analysis on 80 gut microbiotas of 44 mothers.
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Engineering butyrate-producing Lachnospiraceae to treat metabolic disease

Abstract Engineering native gut bacteria offers a route to persistent, programmable therapeutics, yet many dominant taxa remain genetically intractable. Lachnospiraceae are a prevalent and abundant family in the human gut microbiome, possessing metabolic functions generally associated with health 1
Jack Arnold, Sandra McClure, Joshua Glazier, Recep E. Ahan, Sadiksha Shakya, David Villegas, Tracy Leidan Chen, Jay Fuerte-Stone, Rory McGann, Mark Mimee   +9 more
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Gut commensal Lachnospiraceae bacteria contribute to anti-colitis effects of Lactiplantibacillus plantarum exopolysaccharides

International Journal of Biological Macromolecules
The probiotic Lactiplantibacillus plantarum (L. plantarum) could ameliorate colitis. Alterations in the composition of gut microbiota (GM) have been proved in cases of colitis. The exopolysaccharides from L. plantarum HMPM2111 (LPE) could be effective in colitis through altering the composition of the GM.
Jian, Yang, Huijuan, Ren, Jialing, Cao, Jingjing, Fu, Junhui, Wang, Ziwei, Su, Shiqi, Lu, Kangliang, Sheng, Yongzhong, Wang   +8 more
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Lachnospiraceae Engineering and Biosynthetic Chassis Development with Novel Genetic Tools

The human microbiome is intrinsically linked to human health and the progression of various disease states. Until recently, we have been limited by molecular and computational tools to probe many of the bacteria that reside in our intestinal tracts.
openaire   +1 more source