Results 21 to 30 of about 43,463 (274)

Lachnospiraceae-bacterium alleviates ischemia-reperfusion injury in steatotic donor liver by inhibiting ferroptosis via the Foxo3-Alox15 signaling pathway

open access: goldGut Microbes
Ischemia-reperfusion injury (IRI) is a major obstacle in liver transplantation, especially with steatotic donor livers. Dysbiosis of the gut microbiota has been implicated in modulating IRI, and Lachnospiraceae plays a pivotal role in regulating host ...
Shenghe Deng   +14 more
doaj   +2 more sources

Dietary butyrate ameliorates metabolic health associated with selective proliferation of gut Lachnospiraceae bacterium 28-4 [PDF]

open access: goldJCI Insight, 2023
Short-chain fatty acids, including butyrate, have multiple metabolic benefits in individuals who are lean but not in individuals with metabolic syndrome, with the underlying mechanisms still being unclear. We aimed to investigate the role of gut microbiota in the induction of metabolic benefits of dietary butyrate.
Zhuang Li   +17 more
openalex   +9 more sources

Isolation of potentially novel species expands the genomic and functional diversity of Lachnospiraceae [PDF]

open access: yesiMeta
The Lachnospiraceae family holds promise as a source of next‐generation probiotics, yet a comprehensive delineation of its diversity is lacking, hampering the identification of suitable strains for future applications.
Xiaoqian Lin   +15 more
doaj   +4 more sources

The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
A Salonen   +48 more
core   +27 more sources

Genetic Drift and Host-Adaptive Features Likely Underlie the Cladogenesis of Insect-Associated Lachnospiraceae [PDF]

open access: goldGenome Biology and Evolution, 2022
Abstract Phylogenetic and functional group analyses of the genomes of anaerobic bacteria isolated from Periplaneta americana digestive tracts suggest that they represent novel Lachnospiraceae genera. PAL113 and PAL227 isolate genomes encoded short-chain fatty acid biosynthetic pathways and plant fiber and chitin catabolism and other ...
Arturo Vera‐Ponce de León   +6 more
openalex   +3 more sources

Expansion of and reclassification within the family Lachnospiraceae

open access: green, 2021
The anaerobic mesophilic bacterium Clostridium phytofermentans grows and ferments multiple plant-based substrates into ethanol as the main product of fermentation. The capacity of C. phytofermentans to convert plant biomass into ethanol, propanol, and short-chain fatty acids is strongly attractive for industry. Specific physiological capabilities of C.
Kelly Haas
openalex   +3 more sources

Fiber-Associated Lachnospiraceae Reduce Colon Tumorigenesis by Modulation of the Tumor-Immune Microenvironment

open access: greenSSRN Electronic Journal, 2021
Despite increasing evidence implicating the gut microbiome in CRC, the collective role of different microbial consortia in CRC carcinogenesis is unclear. We have previously described these consortia as co-abundance groups that co-exist at different abundance levels in the same patient. Here, we report that tumor biopsy tissue from patients with a “high-
Ana S. Almeida   +14 more
openalex   +2 more sources

The Alteration of Akkermansiaceae/Lachnospiraceae Ratio Is a Microbial Feature of Antibiotic-Induced Microbiota Remodeling

open access: goldBioinformatics and Biology Insights, 2023
Antibiotic treatment has been shown to cause gut microbiota dysbiosis. However, lacking critical features defining gut microbiota dysbiosis makes it challenging to prevent. By co-occurrence network analysis, we found that despite short antibiotic courses eliminating certain microbial taxa, the Akkermansia genus played the role of a high-centrality hub
Pei-Chen Chen   +4 more
openalex   +4 more sources

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